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Biosensing platform based on fluorescence resonance energy transfer from upconverting nanocrystals to graphene oxide

  • Cuiling Zhang
  • , Yunxia Yuan
  • , Shiming Zhang
  • , Yuhui Wang
  • , Zhihong Liu*
  • *Corresponding author for this work
  • Wuhan University

Research output: Contribution to journalArticlepeer-review

Abstract

A glucose sensor based on FRET between concanavalin A (ConA)-labeled upconverting phosphor (UCP) nanocrystals and chitosan (CS)-labeled graphene oxide (GO) is presented. Binding of ConA to CS quenches the fluorescence of UCP, which is restored in the presence of glucose, owing to competition between glucose and CS for ConA (see picture).

Original languageEnglish
Pages (from-to)6851-6854
Number of pages4
JournalAngewandte Chemie - International Edition
Volume50
Issue number30
DOIs
StatePublished - 18 Jul 2011
Externally publishedYes

Keywords

  • FRET
  • analytical methods
  • biosensors
  • graphene
  • nanoparticles

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