Bioactive phenolics and terpenoids from Manglietia insignis

Shan Zhai Shang; Ling Mei Kong; Li Ping Yang; Jing Jiang; Jin Huang; Hai Bo Zhang; Yi Ming Shi; Wei Zhao; Hong Lin Li; Huai Rong Luo; Yan Li; Wei Lie Xiao; Han Dong Sun

doi:10.1016/j.fitote.2012.10.010

Bioactive phenolics and terpenoids from Manglietia insignis

Shan Zhai Shang
, Ling Mei Kong
, Li Ping Yang
, Jing Jiang
, Jin Huang
, Hai Bo Zhang
, Yi Ming Shi
, Wei Zhao
, Hong Lin Li
, Huai Rong Luo
, Yan Li
, Wei Lie Xiao^*
, Han Dong Sun

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

Four new compounds, maninsigins A-D (1-4), including two new neolignans (1-2) and two new sesquiterpenes (3-4), as well as ten known compounds (5-14), were isolated from the leaves and stems of Manglietia insignis. Their structures were established on the basis of extensive spectroscopic analyses. In addition, some compounds were tested for their cytotoxic and neurite outgrowth-promoting activities, as well as their antagonistic activity toward FXR ligand.

Original language	English
Pages (from-to)	58-63
Number of pages	6
Journal	Fitoterapia
Volume	84
Issue number	1
DOIs	https://doi.org/10.1016/j.fitote.2012.10.010
State	Published - Jan 2013
Externally published	Yes

Keywords

Bioactivity
Magnoliaceae
Manglietia insignis
Neolignan
Sesquiterpene

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10.1016/j.fitote.2012.10.010

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title = "Bioactive phenolics and terpenoids from Manglietia insignis",

abstract = "Four new compounds, maninsigins A-D (1-4), including two new neolignans (1-2) and two new sesquiterpenes (3-4), as well as ten known compounds (5-14), were isolated from the leaves and stems of Manglietia insignis. Their structures were established on the basis of extensive spectroscopic analyses. In addition, some compounds were tested for their cytotoxic and neurite outgrowth-promoting activities, as well as their antagonistic activity toward FXR ligand.",

keywords = "Bioactivity, Magnoliaceae, Manglietia insignis, Neolignan, Sesquiterpene",

author = "Shang, \{Shan Zhai\} and Kong, \{Ling Mei\} and Yang, \{Li Ping\} and Jing Jiang and Jin Huang and Zhang, \{Hai Bo\} and Shi, \{Yi Ming\} and Wei Zhao and Li, \{Hong Lin\} and Luo, \{Huai Rong\} and Yan Li and Xiao, \{Wei Lie\} and Sun, \{Han Dong\}",

year = "2013",

month = jan,

doi = "10.1016/j.fitote.2012.10.010",

language = "英语",

volume = "84",

pages = "58--63",

journal = "Fitoterapia",

issn = "0367-326X",

publisher = "Elsevier B.V.",

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}

TY - JOUR

T1 - Bioactive phenolics and terpenoids from Manglietia insignis

AU - Shang, Shan Zhai

AU - Kong, Ling Mei

AU - Yang, Li Ping

AU - Jiang, Jing

AU - Huang, Jin

AU - Zhang, Hai Bo

AU - Shi, Yi Ming

AU - Zhao, Wei

AU - Li, Hong Lin

AU - Luo, Huai Rong

AU - Li, Yan

AU - Xiao, Wei Lie

AU - Sun, Han Dong

PY - 2013/1

Y1 - 2013/1

N2 - Four new compounds, maninsigins A-D (1-4), including two new neolignans (1-2) and two new sesquiterpenes (3-4), as well as ten known compounds (5-14), were isolated from the leaves and stems of Manglietia insignis. Their structures were established on the basis of extensive spectroscopic analyses. In addition, some compounds were tested for their cytotoxic and neurite outgrowth-promoting activities, as well as their antagonistic activity toward FXR ligand.

AB - Four new compounds, maninsigins A-D (1-4), including two new neolignans (1-2) and two new sesquiterpenes (3-4), as well as ten known compounds (5-14), were isolated from the leaves and stems of Manglietia insignis. Their structures were established on the basis of extensive spectroscopic analyses. In addition, some compounds were tested for their cytotoxic and neurite outgrowth-promoting activities, as well as their antagonistic activity toward FXR ligand.

KW - Bioactivity

KW - Magnoliaceae

KW - Manglietia insignis

KW - Neolignan

KW - Sesquiterpene

UR - https://www.scopus.com/pages/publications/84873347747

U2 - 10.1016/j.fitote.2012.10.010

DO - 10.1016/j.fitote.2012.10.010

M3 - 文章

C2 - 23103294

AN - SCOPUS:84873347747

SN - 0367-326X

VL - 84

SP - 58

EP - 63

JO - Fitoterapia

JF - Fitoterapia

IS - 1

ER -

Bioactive phenolics and terpenoids from Manglietia insignis

Abstract

Keywords

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