Asymmetric sequential Au(i)/chiral tertiary amine catalysis: An enone-formation/cyanosilylation sequence to synthesize optically active 3-alkenyloxindoles from diazooxindoles

  • Yu Lei Zhao
  • , Zhong Yan Cao
  • , Xing Ping Zeng
  • , Jia Meng Shi
  • , Yi Hua Yu
  • , Jian Zhou*
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

59 Scopus citations

Abstract

An unprecedented sequential gold-catalyzed enone-formation and bifunctional tertiary amine mediated asymmetric cyanosilylation reaction is developed, allowing the highly enantioselective synthesis of 3-alkenyloxindoles from diazooxindoles, furans and trimethylsilyl cyanide (TMSCN).

Original languageEnglish
Pages (from-to)3943-3946
Number of pages4
JournalChemical Communications
Volume52
Issue number20
DOIs
StatePublished - 2016

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