Asymmetric electrocarboxylation of 1-phenylethyl chloride catalyzed by electrogenerated chiral [CoI(salen)]- complex

Bao Li Chen; Hong Wei Zhu; Yan Xiao; Qi Long Sun; Huan Wang; Jia Xing Lu

doi:10.1016/j.elecom.2014.02.009

Asymmetric electrocarboxylation of 1-phenylethyl chloride catalyzed by electrogenerated chiral [Co^I(salen)]^- complex

Bao Li Chen, Hong Wei Zhu, Yan Xiao, Qi Long Sun, Huan Wang^*, Jia Xing Lu

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

94 Scopus citations

Abstract

The feasibility of asymmetric electrocarboxylation of 1-phenylethyl chloride catalyzed by the electrogenerated chiral [Co^I(salen)] ^- complex has been investigated for the first time. Using this system, optically active 2-phenylpropionic acid in 37% yield and 83% ee is synthesized from 1-phenylethyl chloride and CO₂. The electrochemical behavior of the catalyst and the optimization of synthesis conditions are discussed. This study provides a new procedure for the asymmetric synthesis of a chiral compound and expands the applications of chiral Co^II(salen) in the electrochemical asymmetric fixation of CO₂.

Original language	English
Pages (from-to)	55-59
Number of pages	5
Journal	Electrochemistry Communications
Volume	42
DOIs	https://doi.org/10.1016/j.elecom.2014.02.009
State	Published - May 2014

Keywords

1-Phenylethyl chloride
Asymmetry
Electrocarboxylation

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10.1016/j.elecom.2014.02.009

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title = "Asymmetric electrocarboxylation of 1-phenylethyl chloride catalyzed by electrogenerated chiral [CoI(salen)]- complex",

abstract = "The feasibility of asymmetric electrocarboxylation of 1-phenylethyl chloride catalyzed by the electrogenerated chiral [CoI(salen)] - complex has been investigated for the first time. Using this system, optically active 2-phenylpropionic acid in 37\% yield and 83\% ee is synthesized from 1-phenylethyl chloride and CO2. The electrochemical behavior of the catalyst and the optimization of synthesis conditions are discussed. This study provides a new procedure for the asymmetric synthesis of a chiral compound and expands the applications of chiral CoII(salen) in the electrochemical asymmetric fixation of CO2.",

keywords = "1-Phenylethyl chloride, Asymmetry, Electrocarboxylation",

author = "Chen, \{Bao Li\} and Zhu, \{Hong Wei\} and Yan Xiao and Sun, \{Qi Long\} and Huan Wang and Lu, \{Jia Xing\}",

year = "2014",

month = may,

doi = "10.1016/j.elecom.2014.02.009",

language = "英语",

volume = "42",

pages = "55--59",

journal = "Electrochemistry Communications",

issn = "1388-2481",

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TY - JOUR

T1 - Asymmetric electrocarboxylation of 1-phenylethyl chloride catalyzed by electrogenerated chiral [CoI(salen)]- complex

AU - Chen, Bao Li

AU - Zhu, Hong Wei

AU - Xiao, Yan

AU - Sun, Qi Long

AU - Wang, Huan

AU - Lu, Jia Xing

PY - 2014/5

Y1 - 2014/5

N2 - The feasibility of asymmetric electrocarboxylation of 1-phenylethyl chloride catalyzed by the electrogenerated chiral [CoI(salen)] - complex has been investigated for the first time. Using this system, optically active 2-phenylpropionic acid in 37% yield and 83% ee is synthesized from 1-phenylethyl chloride and CO2. The electrochemical behavior of the catalyst and the optimization of synthesis conditions are discussed. This study provides a new procedure for the asymmetric synthesis of a chiral compound and expands the applications of chiral CoII(salen) in the electrochemical asymmetric fixation of CO2.

AB - The feasibility of asymmetric electrocarboxylation of 1-phenylethyl chloride catalyzed by the electrogenerated chiral [CoI(salen)] - complex has been investigated for the first time. Using this system, optically active 2-phenylpropionic acid in 37% yield and 83% ee is synthesized from 1-phenylethyl chloride and CO2. The electrochemical behavior of the catalyst and the optimization of synthesis conditions are discussed. This study provides a new procedure for the asymmetric synthesis of a chiral compound and expands the applications of chiral CoII(salen) in the electrochemical asymmetric fixation of CO2.

KW - 1-Phenylethyl chloride

KW - Asymmetry

KW - Electrocarboxylation

UR - https://www.scopus.com/pages/publications/84896302020

U2 - 10.1016/j.elecom.2014.02.009

DO - 10.1016/j.elecom.2014.02.009

M3 - 文章

AN - SCOPUS:84896302020

SN - 1388-2481

VL - 42

SP - 55

EP - 59

JO - Electrochemistry Communications

JF - Electrochemistry Communications

ER -

Asymmetric electrocarboxylation of 1-phenylethyl chloride catalyzed by electrogenerated chiral [Co^I(salen)]^- complex

Abstract

Keywords

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