Asymmetric construction of quaternary stereocenters by direct organocatalytic amination of 3-substituted oxindoles

Zi Qing Qian; Feng Zhou; Tai Ping Du; Bo Lun Wang; Miao Ding; Xiao Li Zhao; Jian Zhou

doi:10.1039/b915257a

Asymmetric construction of quaternary stereocenters by direct organocatalytic amination of 3-substituted oxindoles

Zi Qing Qian
, Feng Zhou
, Tai Ping Du
, Bo Lun Wang
, Miao Ding
, Xiao Li Zhao
, Jian Zhou^*

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

Research output: Contribution to journal › Article › peer-review

169 Scopus citations

Abstract

Quinidine derivative (QD)₂PYR was found to catalyze the asymmetric direct amination of unprotected prochiral 3-oxindole with DIAD to construct quaternary stereocenters at the C3 position with excellent enantioselectivity.

Original language	English
Pages (from-to)	6753-6755
Number of pages	3
Journal	Chemical Communications
Issue number	44
DOIs	https://doi.org/10.1039/b915257a
State	Published - 2009

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10.1039/b915257a

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@article{1f6337e79608473e908e7aeda7ae3094,

title = "Asymmetric construction of quaternary stereocenters by direct organocatalytic amination of 3-substituted oxindoles",

abstract = "Quinidine derivative (QD)2PYR was found to catalyze the asymmetric direct amination of unprotected prochiral 3-oxindole with DIAD to construct quaternary stereocenters at the C3 position with excellent enantioselectivity.",

author = "Qian, \{Zi Qing\} and Feng Zhou and Du, \{Tai Ping\} and Wang, \{Bo Lun\} and Miao Ding and Zhao, \{Xiao Li\} and Jian Zhou",

year = "2009",

doi = "10.1039/b915257a",

language = "英语",

pages = "6753--6755",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "44",

}

TY - JOUR

T1 - Asymmetric construction of quaternary stereocenters by direct organocatalytic amination of 3-substituted oxindoles

AU - Qian, Zi Qing

AU - Zhou, Feng

AU - Du, Tai Ping

AU - Wang, Bo Lun

AU - Ding, Miao

AU - Zhao, Xiao Li

AU - Zhou, Jian

PY - 2009

Y1 - 2009

N2 - Quinidine derivative (QD)2PYR was found to catalyze the asymmetric direct amination of unprotected prochiral 3-oxindole with DIAD to construct quaternary stereocenters at the C3 position with excellent enantioselectivity.

AB - Quinidine derivative (QD)2PYR was found to catalyze the asymmetric direct amination of unprotected prochiral 3-oxindole with DIAD to construct quaternary stereocenters at the C3 position with excellent enantioselectivity.

UR - https://www.scopus.com/pages/publications/70449371812

U2 - 10.1039/b915257a

DO - 10.1039/b915257a

M3 - 文章

C2 - 19885468

AN - SCOPUS:70449371812

SN - 1359-7345

SP - 6753

EP - 6755

JO - Chemical Communications

JF - Chemical Communications

IS - 44

ER -

Asymmetric construction of quaternary stereocenters by direct organocatalytic amination of 3-substituted oxindoles

Abstract

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