An unusual synthesis of Tröger's bases using DMSO/HCl as formaldehyde equivalent

  • Zhong Li*
  • , Xiaoyong Xu
  • , Yanqing Peng
  • , Zhaoxing Jiang
  • , Chuanyong Ding
  • , Xuhong Qian
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

52 Scopus citations

Abstract

The reactions between anilines and DMSO/HCl produce Tröger's bases in moderate yield. The Tröger's bases bearing an electron-withdrawing group can also be synthesized through this procedure. In this reaction, DMSO/HCl acts as formaldehyde equivalent.

Original languageEnglish
Pages (from-to)1228-1230
Number of pages3
JournalSynthesis (Germany)
Issue number8
DOIs
StatePublished - 20 May 2005
Externally publishedYes

Keywords

  • DMSO/HCl
  • Formaldehyde equivalent
  • Tröger's bases

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