An organosilane route to mesoporous silica nanoparticles with tunable particle and pore sizes and their anticancer drug delivery behavior

Wenru Zhao; Hongti Zhang; Shu Chang; Jinlou Gu; Yongsheng Li; Liang Li; Jianlin Shi

doi:10.1039/c2ra20166f

An organosilane route to mesoporous silica nanoparticles with tunable particle and pore sizes and their anticancer drug delivery behavior

Wenru Zhao, Hongti Zhang, Shu Chang, Jinlou Gu, Yongsheng Li, Liang Li, Jianlin Shi

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Uniform mesoporous silica nanospheres were synthesized using organosilane as a template. By adjusting the water/ethanol ratio and the amount of the silica precursors, the pore and particle sizes can be tuned in a certain range. The materials show a sustained and pH-sensitive drug release property and a comparable antitumor efficacy.

Original language	English
Pages (from-to)	5105-5107
Number of pages	3
Journal	RSC Advances
Volume	2
Issue number	12
DOIs	https://doi.org/10.1039/c2ra20166f
State	Published - 21 Jun 2012
Externally published	Yes

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10.1039/c2ra20166f

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title = "An organosilane route to mesoporous silica nanoparticles with tunable particle and pore sizes and their anticancer drug delivery behavior",

abstract = "Uniform mesoporous silica nanospheres were synthesized using organosilane as a template. By adjusting the water/ethanol ratio and the amount of the silica precursors, the pore and particle sizes can be tuned in a certain range. The materials show a sustained and pH-sensitive drug release property and a comparable antitumor efficacy.",

author = "Wenru Zhao and Hongti Zhang and Shu Chang and Jinlou Gu and Yongsheng Li and Liang Li and Jianlin Shi",

year = "2012",

month = jun,

day = "21",

doi = "10.1039/c2ra20166f",

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T1 - An organosilane route to mesoporous silica nanoparticles with tunable particle and pore sizes and their anticancer drug delivery behavior

AU - Zhao, Wenru

AU - Zhang, Hongti

AU - Chang, Shu

AU - Gu, Jinlou

AU - Li, Yongsheng

AU - Li, Liang

AU - Shi, Jianlin

PY - 2012/6/21

Y1 - 2012/6/21

N2 - Uniform mesoporous silica nanospheres were synthesized using organosilane as a template. By adjusting the water/ethanol ratio and the amount of the silica precursors, the pore and particle sizes can be tuned in a certain range. The materials show a sustained and pH-sensitive drug release property and a comparable antitumor efficacy.

AB - Uniform mesoporous silica nanospheres were synthesized using organosilane as a template. By adjusting the water/ethanol ratio and the amount of the silica precursors, the pore and particle sizes can be tuned in a certain range. The materials show a sustained and pH-sensitive drug release property and a comparable antitumor efficacy.

UR - https://www.scopus.com/pages/publications/84880911677

U2 - 10.1039/c2ra20166f

DO - 10.1039/c2ra20166f

M3 - 文章

AN - SCOPUS:84880911677

SN - 2046-2069

VL - 2

SP - 5105

EP - 5107

JO - RSC Advances

JF - RSC Advances

IS - 12

ER -

An organosilane route to mesoporous silica nanoparticles with tunable particle and pore sizes and their anticancer drug delivery behavior

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