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An organosilane route to mesoporous silica nanoparticles with tunable particle and pore sizes and their anticancer drug delivery behavior

  • Wenru Zhao
  • , Hongti Zhang
  • , Shu Chang
  • , Jinlou Gu
  • , Yongsheng Li
  • , Liang Li
  • , Jianlin Shi*
  • *Corresponding author for this work
  • East China University of Science and Technology
  • CAS - Shanghai Institute of Ceramics

Research output: Contribution to journalArticlepeer-review

Abstract

Uniform mesoporous silica nanospheres were synthesized using organosilane as a template. By adjusting the water/ethanol ratio and the amount of the silica precursors, the pore and particle sizes can be tuned in a certain range. The materials show a sustained and pH-sensitive drug release property and a comparable antitumor efficacy.

Original languageEnglish
Pages (from-to)5105-5107
Number of pages3
JournalRSC Advances
Volume2
Issue number12
DOIs
StatePublished - 21 Jun 2012
Externally publishedYes

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