Abstract
The development of a simple, sensitive, selective, and stable amperometric nitric oxide microsensor is described. It is based on Ni(chitin)2 mediators immobilized on a platinum, Nafion modified electrode. The detection of NO is based on the Ni(chitin)2 catalysis of NO oxidation at an anodic potential of +0.74 V (vs. SCE). The catalytic peak current is linear for a NO concentration in the range of 8.5 × 10-8 mol/L to 1.5 × 10-5 mol/L, with a correlation coefficient of 0.9992. The detection limit of the microsensor is 5.0 × 10-8 mol/L. It is suitable for the direct measurement of NO in biological systems.
| Original language | English |
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| Pages (from-to) | 587-591 |
| Number of pages | 5 |
| Journal | Analytical and Bioanalytical Chemistry |
| Volume | 365 |
| Issue number | 7 |
| DOIs | |
| State | Published - 1999 |