An Ni(chitin)2 modified nitric oxide microsensor

  • Yuezhong Xian
  • , Jian Xue
  • , Song Zhang
  • , Xiangyang Ying
  • , Litong Jin*
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

The development of a simple, sensitive, selective, and stable amperometric nitric oxide microsensor is described. It is based on Ni(chitin)2 mediators immobilized on a platinum, Nafion modified electrode. The detection of NO is based on the Ni(chitin)2 catalysis of NO oxidation at an anodic potential of +0.74 V (vs. SCE). The catalytic peak current is linear for a NO concentration in the range of 8.5 × 10-8 mol/L to 1.5 × 10-5 mol/L, with a correlation coefficient of 0.9992. The detection limit of the microsensor is 5.0 × 10-8 mol/L. It is suitable for the direct measurement of NO in biological systems.

Original languageEnglish
Pages (from-to)587-591
Number of pages5
JournalAnalytical and Bioanalytical Chemistry
Volume365
Issue number7
DOIs
StatePublished - 1999

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