An ESIPT-based fluorescent probe for sensitive detection of hydrazine in aqueous solution

Ji Zhou; Ruiyan Shi; Jianxu Liu; Rui Wang; Yufang Xu; Xuhong Qian

doi:10.1039/c5ob00209e

An ESIPT-based fluorescent probe for sensitive detection of hydrazine in aqueous solution

Ji Zhou, Ruiyan Shi, Jianxu Liu, Rui Wang, Yufang Xu, Xuhong Qian

East China University of Science and Technology

Research output: Contribution to journal › Article › peer-review

69 Scopus citations

Abstract

A fluorescent probe for sensitive detection of hydrazine based on an ESIPT mechanism and a substitution-cyclization-elimination cascade was developed. After the addition of hydrazine, an approximately 50-fold enhancement in fluorescence intensity at 465 nm was observed and the subsequent decrease at 375 nm was observed in 10 min with a detection limit of 0.147 μM. We also detected hydrazine in HeLa cells successfully.

Original language	English
Pages (from-to)	5344-5348
Number of pages	5
Journal	Organic and Biomolecular Chemistry
Volume	13
Issue number	19
DOIs	https://doi.org/10.1039/c5ob00209e
State	Published - 21 May 2015
Externally published	Yes

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abstract = "A fluorescent probe for sensitive detection of hydrazine based on an ESIPT mechanism and a substitution-cyclization-elimination cascade was developed. After the addition of hydrazine, an approximately 50-fold enhancement in fluorescence intensity at 465 nm was observed and the subsequent decrease at 375 nm was observed in 10 min with a detection limit of 0.147 μM. We also detected hydrazine in HeLa cells successfully.",

author = "Ji Zhou and Ruiyan Shi and Jianxu Liu and Rui Wang and Yufang Xu and Xuhong Qian",

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AU - Zhou, Ji

AU - Shi, Ruiyan

AU - Liu, Jianxu

AU - Wang, Rui

AU - Xu, Yufang

AU - Qian, Xuhong

N1 - Publisher Copyright: © The Royal Society of Chemistry 2015.

PY - 2015/5/21

Y1 - 2015/5/21

N2 - A fluorescent probe for sensitive detection of hydrazine based on an ESIPT mechanism and a substitution-cyclization-elimination cascade was developed. After the addition of hydrazine, an approximately 50-fold enhancement in fluorescence intensity at 465 nm was observed and the subsequent decrease at 375 nm was observed in 10 min with a detection limit of 0.147 μM. We also detected hydrazine in HeLa cells successfully.

AB - A fluorescent probe for sensitive detection of hydrazine based on an ESIPT mechanism and a substitution-cyclization-elimination cascade was developed. After the addition of hydrazine, an approximately 50-fold enhancement in fluorescence intensity at 465 nm was observed and the subsequent decrease at 375 nm was observed in 10 min with a detection limit of 0.147 μM. We also detected hydrazine in HeLa cells successfully.

UR - https://www.scopus.com/pages/publications/84929103524

U2 - 10.1039/c5ob00209e

DO - 10.1039/c5ob00209e

M3 - 文章

C2 - 25869440

AN - SCOPUS:84929103524

SN - 1477-0520

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JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 19

ER -

An ESIPT-based fluorescent probe for sensitive detection of hydrazine in aqueous solution

Abstract

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