An efficient synthesis of 2-chloropyrimidines via Pd-catalyzed regioselective dechlorination of 2,4-dichloropyrimidines in the presence of NaHCO3

  • Yang Ming Zhang*
  • , Min Gu
  • , Hui Ma
  • , Jie Tang
  • , Wei Lu
  • , Fa Jun Nan
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

An efficient synthesis of 2-chloropyrimidines from readily accessible 2,4-dichloropyrimidines was achieved via Pd-catalyzed regioselective dechlorination in the presence NaHCO3.

Original languageEnglish
Pages (from-to)962-964
Number of pages3
JournalChinese Journal of Chemistry
Volume26
Issue number5
DOIs
StatePublished - May 2008

Keywords

  • 2,4-dichloropyrimidine
  • 2-chloropyrimidine
  • Catalytic hydrogenation
  • Palladium on carbon

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