An efficient and mild CuI/L-proline-catalyzed arylation of acetylacetone or ethyl cyanoacetate

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Abstract

The coupling reaction of aryl iodides with acetylacetone or ethyl cyanoacetate under catalysis of CuI/L-proline works at relatively mild conditions to provide 3-aryl-2, 4-pentanediones and α-aryl cyanoacetates in moderate to good yields.

Original languageEnglish
Article numberU24705ST
Pages (from-to)2731-2734
Number of pages4
JournalSynlett
Issue number18
DOIs
StatePublished - 3 Nov 2005

Keywords

  • Additive
  • Aryl iodide
  • Arylation
  • Catalysis
  • Cross coupling

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