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Alkaloid induced asymmetric electrocarboxylation of 4-methylpropiophenone

  • Shu Feng Zhao
  • , Mei Xia Zhu
  • , Kai Zhang
  • , Huan Wang*
  • , Jia Xing Lu
  • *Corresponding author for this work
  • East China Normal University

Research output: Contribution to journal › Article › peer-review

Abstract

The alkaloid-induced electrocarboxylation of 4-methylpropiophenone is examined in mild conditions. Comparative studies with several inductors indicate that the efficient enantiodiscrimination of the electrocarboxylation depends on the nucleophilic quinuclidine nitrogen atom and the OH group of the inductors.

Original languageEnglish
Pages (from-to)2702-2705
Number of pages4
JournalTetrahedron Letters
Volume52
Issue number21
DOIs
StatePublished - 25 May 2011

Keywords

  • Carbon dioxide
  • Cinchonine
  • Electrocarboxylation
  • Enantiomeric excess
  • Induction

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