Advances in surface plasmon resonance-based high throughput biochips

San jun Zhang, Lotfi Berguiga, Juan Elezgaray, Nicolas Hugo, Wen xue Li, Thibault Roland, He ping Zeng, Francoise Argoul

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations

Abstract

This article reviews our recent advances in surface plasmon resonance (SPR) based biochips. It includes four issues, which are the preparation and characterization of high quality gold film, the preparation and characterization of self-assembled monolayer (SAM), dynamics of DNA adsorption on SAMs, and SPR-based microscopies. Numerous topics related to SPR, such as, the modeling of SPR by transmission matrix, effective medium theory, applications of SPR in biology, and SPR-based novel microscopies, are discussed. A novel electrochemical technique, which is extremely useful for the preparation and characterization of high quality SAMs, is also discussed.

Original languageEnglish
Pages (from-to)469-480
Number of pages12
JournalFrontiers of Physics in China
Volume4
Issue number4
DOIs
StatePublished - Sep 2009

Keywords

  • Atomic force microscopy
  • Effective medium theory
  • Electrochemical impedance spectroscopy
  • SPR-based microscopy
  • Self-assembled monolayer
  • Surface plasmon resonance

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