Advances in research and applications of CRISPR

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats), one of rapidly developing genome editing technologies, has been successfully applied in many organisms, including diseases models, animals and crop plants. Compared with previous techniques such as ZENs and TALENs, the CRISPR shows distinct advantages in editing multiple genes simultaneously in the same cell. Therefore, currently genome editing experiments have been widely performed by using CRISPR technology. Advances in research and applications of CRISPR include disease research, gene therapy, drug target identification and validation, stem cell research, research using model organisms, development of CRISPR-based therapeutics, and so on.

Original languageEnglish
Title of host publicationCRISPR
Subtitle of host publicationAdvances in Research and Applications
PublisherNova Science Publishers, Inc.
Pages1-15
Number of pages15
ISBN (Electronic)9781536129472
ISBN (Print)9781536129465
StatePublished - 1 Jan 2017

Keywords

  • CRISPR
  • Disease research
  • Gene therapy
  • Genome editing
  • Model orgainsms
  • Stem cell research

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