Acridinium benzoates for ratiometric fluorescence imaging of cellular viscosity

Min Wen; Chen Li; Mengyuan Zhang; Yan Sun; Fengming Liu; Xiaoyan Cui; Yongkui Shan

doi:10.1039/d0an02321c

Acridinium benzoates for ratiometric fluorescence imaging of cellular viscosity

Min Wen
, Chen Li
, Mengyuan Zhang
, Yan Sun
, Fengming Liu
, Xiaoyan Cui^*
, Yongkui Shan

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

East China Normal University
National Center for Protein Science Shanghai

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

A series of fluorescent molecular rotors, acridinium benzoates (Acr-A,B,C,D), were designed for ratiometrically monitoring cellular viscosity. High sensitivity to viscosity was observed in probe Acr-A with an insignificant steric effect in the acridinium nitrogen. Acr-A was employed to distinguish cancer cells from normal cells and track the dynamics of viscosity during cellular apoptosis.

Original language	English
Pages (from-to)	1538-1542
Number of pages	5
Journal	Analyst
Volume	146
Issue number	5
DOIs	https://doi.org/10.1039/d0an02321c
State	Published - 7 Mar 2021

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10.1039/d0an02321c

Cite this

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title = "Acridinium benzoates for ratiometric fluorescence imaging of cellular viscosity",

abstract = "A series of fluorescent molecular rotors, acridinium benzoates (Acr-A,B,C,D), were designed for ratiometrically monitoring cellular viscosity. High sensitivity to viscosity was observed in probe Acr-A with an insignificant steric effect in the acridinium nitrogen. Acr-A was employed to distinguish cancer cells from normal cells and track the dynamics of viscosity during cellular apoptosis.",

author = "Min Wen and Chen Li and Mengyuan Zhang and Yan Sun and Fengming Liu and Xiaoyan Cui and Yongkui Shan",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry.",

year = "2021",

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doi = "10.1039/d0an02321c",

language = "英语",

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T1 - Acridinium benzoates for ratiometric fluorescence imaging of cellular viscosity

AU - Wen, Min

AU - Li, Chen

AU - Zhang, Mengyuan

AU - Sun, Yan

AU - Liu, Fengming

AU - Cui, Xiaoyan

AU - Shan, Yongkui

PY - 2021/3/7

Y1 - 2021/3/7

N2 - A series of fluorescent molecular rotors, acridinium benzoates (Acr-A,B,C,D), were designed for ratiometrically monitoring cellular viscosity. High sensitivity to viscosity was observed in probe Acr-A with an insignificant steric effect in the acridinium nitrogen. Acr-A was employed to distinguish cancer cells from normal cells and track the dynamics of viscosity during cellular apoptosis.

AB - A series of fluorescent molecular rotors, acridinium benzoates (Acr-A,B,C,D), were designed for ratiometrically monitoring cellular viscosity. High sensitivity to viscosity was observed in probe Acr-A with an insignificant steric effect in the acridinium nitrogen. Acr-A was employed to distinguish cancer cells from normal cells and track the dynamics of viscosity during cellular apoptosis.

UR - https://www.scopus.com/pages/publications/85102207735

U2 - 10.1039/d0an02321c

DO - 10.1039/d0an02321c

M3 - 文章

C2 - 33522524

AN - SCOPUS:85102207735

SN - 0003-2654

VL - 146

SP - 1538

EP - 1542

JO - Analyst

JF - Analyst

IS - 5

ER -

Acridinium benzoates for ratiometric fluorescence imaging of cellular viscosity

Abstract

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