Abstract
Objective: To explore an accurate way of describing the metabolic process of magnetic resonance contrast agent in naked mouse. Methods: Firstly, the data of signal-to-noise ratio (SNR) were derived from DICOM files, and their sequential accurate times after contrast agent injection were acquired from the DICOM Header with a Matlab program. The spatial correction factor of the surface coil axial direction was calculated from the images of a water phantom, which was used to correct the SNR of the metabolic organ. Results: The metabolic process of naked mouse livers were depicted by four kinds of metabolic curves (signal intensity, SNR, signal intensity enhancement rate and SNR enhancement rate). Conclusion: Metabolic curve of SNR enhancement rate after accurate time and spatial correction can best represent the metabolic process of magnetic resonance contrast agent in vivo organ.
| Original language | English |
|---|---|
| Pages (from-to) | 320-324 |
| Number of pages | 5 |
| Journal | Chinese Journal of Interventional Imaging and Therapy |
| Volume | 7 |
| Issue number | 3 |
| State | Published - May 2010 |
Keywords
- Contrast agent
- Magnetic resonance imaging
- Metabolism curve
- Spatial correction
- Surface coil