Abiestetranes A and B, two unique tetraterpenes from Abies fabri

Yong Li Li; Shou De Zhang; Hui Zi Jin; Jun Mian Tian; Yun Heng Shen; Xian Wen Yang; Hong Lin Li; Wei Dong Zhang

doi:10.1016/j.tet.2012.07.047

Abiestetranes A and B, two unique tetraterpenes from Abies fabri

Yong Li Li, Shou De Zhang, Hui Zi Jin, Jun Mian Tian, Yun Heng Shen, Xian Wen Yang, Hong Lin Li, Wei Dong Zhang

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Abiestetranes A (1) and B (2), two unique tetraterpenes formed by Diels-Alder cycloaddition between a lanostane triterpenoid and a monoterpenoid, were isolated from Abies fabri. Their structures were elucidated by extensive analysis of NMR data. The electronic circular dichroism was utilized to assign the absolute configuration of 1. Compounds 1 and 2 showed significant cytotoxic activities against ZR-75-30 tumor cell with IC ₅₀ values of 6.26 and 1.63 μg/mL, respectively.

Original language	English
Pages (from-to)	7763-7767
Number of pages	5
Journal	Tetrahedron
Volume	68
Issue number	38
DOIs	https://doi.org/10.1016/j.tet.2012.07.047
State	Published - 23 Sep 2012
Externally published	Yes

Keywords

Abies fabri
Abiestetranes A and B
Cytotoxicity
Diels-Alder cycloaddition
Pinaceae
Tetraterpenes

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10.1016/j.tet.2012.07.047

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title = "Abiestetranes A and B, two unique tetraterpenes from Abies fabri",

abstract = "Abiestetranes A (1) and B (2), two unique tetraterpenes formed by Diels-Alder cycloaddition between a lanostane triterpenoid and a monoterpenoid, were isolated from Abies fabri. Their structures were elucidated by extensive analysis of NMR data. The electronic circular dichroism was utilized to assign the absolute configuration of 1. Compounds 1 and 2 showed significant cytotoxic activities against ZR-75-30 tumor cell with IC 50 values of 6.26 and 1.63 μg/mL, respectively.",

keywords = "Abies fabri, Abiestetranes A and B, Cytotoxicity, Diels-Alder cycloaddition, Pinaceae, Tetraterpenes",

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year = "2012",

month = sep,

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doi = "10.1016/j.tet.2012.07.047",

language = "英语",

volume = "68",

pages = "7763--7767",

journal = "Tetrahedron",

issn = "0040-4020",

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TY - JOUR

T1 - Abiestetranes A and B, two unique tetraterpenes from Abies fabri

AU - Li, Yong Li

AU - Zhang, Shou De

AU - Jin, Hui Zi

AU - Tian, Jun Mian

AU - Shen, Yun Heng

AU - Yang, Xian Wen

AU - Li, Hong Lin

AU - Zhang, Wei Dong

PY - 2012/9/23

Y1 - 2012/9/23

N2 - Abiestetranes A (1) and B (2), two unique tetraterpenes formed by Diels-Alder cycloaddition between a lanostane triterpenoid and a monoterpenoid, were isolated from Abies fabri. Their structures were elucidated by extensive analysis of NMR data. The electronic circular dichroism was utilized to assign the absolute configuration of 1. Compounds 1 and 2 showed significant cytotoxic activities against ZR-75-30 tumor cell with IC 50 values of 6.26 and 1.63 μg/mL, respectively.

AB - Abiestetranes A (1) and B (2), two unique tetraterpenes formed by Diels-Alder cycloaddition between a lanostane triterpenoid and a monoterpenoid, were isolated from Abies fabri. Their structures were elucidated by extensive analysis of NMR data. The electronic circular dichroism was utilized to assign the absolute configuration of 1. Compounds 1 and 2 showed significant cytotoxic activities against ZR-75-30 tumor cell with IC 50 values of 6.26 and 1.63 μg/mL, respectively.

KW - Abies fabri

KW - Abiestetranes A and B

KW - Cytotoxicity

KW - Diels-Alder cycloaddition

KW - Pinaceae

KW - Tetraterpenes

UR - https://www.scopus.com/pages/publications/84864626380

U2 - 10.1016/j.tet.2012.07.047

DO - 10.1016/j.tet.2012.07.047

M3 - 文章

AN - SCOPUS:84864626380

SN - 0040-4020

VL - 68

SP - 7763

EP - 7767

JO - Tetrahedron

JF - Tetrahedron

IS - 38

ER -

Abiestetranes A and B, two unique tetraterpenes from Abies fabri

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Keywords

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