A two-channel ratiometric electrochemical biosensor for in vivo monitoring of copper ions in a rat brain using gold truncated octahedral microcages

Xiaolan Chai, Xinguang Zhou, Anwei Zhu, Limin Zhang, Yao Qin, Guoyue Shi, Yang Tian*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

133 Scopus citations

Abstract

Brain chemistry: A biosensor has been developed for in vivo determination of copper ions in a rat brain by using gold truncated octahedral microcages. The significant analytical performance of the present biosensor, as well as the properties of a carbon fiber microelectrode have provided a direct and reliable approach for monitoring cerebral metal ions (W.E.=working electrode; see picture).

Original languageEnglish
Pages (from-to)8129-8133
Number of pages5
JournalAngewandte Chemie - International Edition
Volume52
Issue number31
DOIs
StatePublished - 29 Jul 2013

Keywords

  • biosensors
  • brain
  • copper ions
  • electrochemistry

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