Abstract
A multiple modeling algorithm for antibiotic fermentation process based on fuzzy c-means (FCM) and support vector regression (SVR) is proposed. By analyzing the features of antibiotic fermentation, the mechanism of multiple modeling of the bioprocess is presented. Using FCM clustering method, the bioprocess is classified into several work states and sub-models. Then, taking advantage of the generalization properties of SVR, the multiple model of bioprocess is established and the proposed algorithm is described. Experimental data of industrial penicillin production is used to validate the model.
| Original language | English |
|---|---|
| Pages (from-to) | 691-696 |
| Number of pages | 6 |
| Journal | Lecture Notes in Computer Science |
| Volume | 3498 |
| Issue number | III |
| DOIs | |
| State | Published - 2005 |
| Externally published | Yes |
| Event | Second International Symposium on Neural Networks: Advances in Neural Networks - ISNN 2005 - Chongqing, China Duration: 30 May 2005 → 1 Jun 2005 |