A stereoselective synthesis of fully substituted tetrahydrofurans through 1,3-dipolar cycloaddition with cinnamaldehydes: An easy access to chroman derivatives

Lin Qiu; Xin Guo; Jun Zhou; Shunying Liu; Liping Yang; Xiang Wu; Wenhao Hu

doi:10.1039/c3ra44123g

A stereoselective synthesis of fully substituted tetrahydrofurans through 1,3-dipolar cycloaddition with cinnamaldehydes: An easy access to chroman derivatives

Lin Qiu, Xin Guo, Jun Zhou, Shunying Liu, Liping Yang, Xiang Wu, Wenhao Hu

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

An efficient method of synthesizing the fully-substituted tetrahydrofuran through intermolecular dipolar cycloaddition reactions of aryl diazoesters, β-nitrostyrenes and cinnamaldehydes was developed. A novel cascade 1,3-dipolar cycloaddition/Michael addition reaction provides a rapid and step-economic construction of highly substituted polycyclic chroman frameworks.

Original language	English
Pages (from-to)	20065-20070
Number of pages	6
Journal	RSC Advances
Volume	3
Issue number	43
DOIs	https://doi.org/10.1039/c3ra44123g
State	Published - 21 Nov 2013

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title = "A stereoselective synthesis of fully substituted tetrahydrofurans through 1,3-dipolar cycloaddition with cinnamaldehydes: An easy access to chroman derivatives",

abstract = "An efficient method of synthesizing the fully-substituted tetrahydrofuran through intermolecular dipolar cycloaddition reactions of aryl diazoesters, β-nitrostyrenes and cinnamaldehydes was developed. A novel cascade 1,3-dipolar cycloaddition/Michael addition reaction provides a rapid and step-economic construction of highly substituted polycyclic chroman frameworks.",

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T1 - A stereoselective synthesis of fully substituted tetrahydrofurans through 1,3-dipolar cycloaddition with cinnamaldehydes

T2 - An easy access to chroman derivatives

AU - Qiu, Lin

AU - Guo, Xin

AU - Zhou, Jun

AU - Liu, Shunying

AU - Yang, Liping

AU - Wu, Xiang

AU - Hu, Wenhao

PY - 2013/11/21

Y1 - 2013/11/21

N2 - An efficient method of synthesizing the fully-substituted tetrahydrofuran through intermolecular dipolar cycloaddition reactions of aryl diazoesters, β-nitrostyrenes and cinnamaldehydes was developed. A novel cascade 1,3-dipolar cycloaddition/Michael addition reaction provides a rapid and step-economic construction of highly substituted polycyclic chroman frameworks.

AB - An efficient method of synthesizing the fully-substituted tetrahydrofuran through intermolecular dipolar cycloaddition reactions of aryl diazoesters, β-nitrostyrenes and cinnamaldehydes was developed. A novel cascade 1,3-dipolar cycloaddition/Michael addition reaction provides a rapid and step-economic construction of highly substituted polycyclic chroman frameworks.

UR - https://www.scopus.com/pages/publications/84886894395

U2 - 10.1039/c3ra44123g

DO - 10.1039/c3ra44123g

M3 - 文章

AN - SCOPUS:84886894395

SN - 2046-2069

VL - 3

SP - 20065

EP - 20070

JO - RSC Advances

JF - RSC Advances

IS - 43

ER -

A stereoselective synthesis of fully substituted tetrahydrofurans through 1,3-dipolar cycloaddition with cinnamaldehydes: An easy access to chroman derivatives

Abstract

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