A stereoselective synthesis of fully substituted tetrahydrofurans through 1,3-dipolar cycloaddition with cinnamaldehydes: An easy access to chroman derivatives

Lin Qiu; Xin Guo; Jun Zhou; Shunying Liu; Liping Yang; Xiang Wu; Wenhao Hu

doi:10.1039/c3ra44123g

A stereoselective synthesis of fully substituted tetrahydrofurans through 1,3-dipolar cycloaddition with cinnamaldehydes: An easy access to chroman derivatives

Lin Qiu
, Xin Guo
, Jun Zhou
, Shunying Liu^*
, Liping Yang
, Xiang Wu
, Wenhao Hu

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

An efficient method of synthesizing the fully-substituted tetrahydrofuran through intermolecular dipolar cycloaddition reactions of aryl diazoesters, β-nitrostyrenes and cinnamaldehydes was developed. A novel cascade 1,3-dipolar cycloaddition/Michael addition reaction provides a rapid and step-economic construction of highly substituted polycyclic chroman frameworks.

Original language	English
Pages (from-to)	20065-20070
Number of pages	6
Journal	RSC Advances
Volume	3
Issue number	43
DOIs	https://doi.org/10.1039/c3ra44123g
State	Published - 21 Nov 2013

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title = "A stereoselective synthesis of fully substituted tetrahydrofurans through 1,3-dipolar cycloaddition with cinnamaldehydes: An easy access to chroman derivatives",

abstract = "An efficient method of synthesizing the fully-substituted tetrahydrofuran through intermolecular dipolar cycloaddition reactions of aryl diazoesters, β-nitrostyrenes and cinnamaldehydes was developed. A novel cascade 1,3-dipolar cycloaddition/Michael addition reaction provides a rapid and step-economic construction of highly substituted polycyclic chroman frameworks.",

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T1 - A stereoselective synthesis of fully substituted tetrahydrofurans through 1,3-dipolar cycloaddition with cinnamaldehydes

T2 - An easy access to chroman derivatives

AU - Qiu, Lin

AU - Guo, Xin

AU - Zhou, Jun

AU - Liu, Shunying

AU - Yang, Liping

AU - Wu, Xiang

AU - Hu, Wenhao

PY - 2013/11/21

Y1 - 2013/11/21

N2 - An efficient method of synthesizing the fully-substituted tetrahydrofuran through intermolecular dipolar cycloaddition reactions of aryl diazoesters, β-nitrostyrenes and cinnamaldehydes was developed. A novel cascade 1,3-dipolar cycloaddition/Michael addition reaction provides a rapid and step-economic construction of highly substituted polycyclic chroman frameworks.

AB - An efficient method of synthesizing the fully-substituted tetrahydrofuran through intermolecular dipolar cycloaddition reactions of aryl diazoesters, β-nitrostyrenes and cinnamaldehydes was developed. A novel cascade 1,3-dipolar cycloaddition/Michael addition reaction provides a rapid and step-economic construction of highly substituted polycyclic chroman frameworks.

UR - https://www.scopus.com/pages/publications/84886894395

U2 - 10.1039/c3ra44123g

DO - 10.1039/c3ra44123g

M3 - 文章

AN - SCOPUS:84886894395

SN - 2046-2069

VL - 3

SP - 20065

EP - 20070

JO - RSC Advances

JF - RSC Advances

IS - 43

ER -

A stereoselective synthesis of fully substituted tetrahydrofurans through 1,3-dipolar cycloaddition with cinnamaldehydes: An easy access to chroman derivatives

Abstract

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