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A simple route to prepare monodisperse Au NP-decorated, dye-doped, superparamagnetic nanocomposites for optical, MR, and CT trimodal imaging

  • Wenjie Dong
  • , Yongsheng Li*
  • , Dechao Niu
  • , Zhi Ma
  • , Xiaohang Liu
  • , Jinlou Gu
  • , Wenru Zhao
  • , Yuanyi Zheng
  • , Jianlin Shi
  • *Corresponding author for this work
  • East China University of Science and Technology
  • CAS - Shanghai Institute of Organic Chemistry
  • Fudan University
  • Chongqing Medical University
  • CAS - Shanghai Institute of Ceramics

Research output: Contribution to journalArticlepeer-review

Abstract

Monodisperse and uniform AuNP-decorated, dye-doped, superparamagnetic nanocomposites (Fe3O4@dye-hybrid@Au) are fabricated by using a simple method in which the Au NP formation and their attachment onto the core surface via S-Au covalent bonds proceeds almost simultaneously in a one-pot synthesis. The as-synthesized nanocomposites can simultaneously enhance the contrast effects for MR, CT, and cellular-sensitive optical imaging.

Original languageEnglish
Pages (from-to)2500-2508
Number of pages9
JournalSmall
Volume9
Issue number15
DOIs
StatePublished - 12 Aug 2013
Externally publishedYes

Keywords

  • computed tomography
  • gold nanoparticles
  • magnetic resonance imaging
  • nanocomposites
  • superparamagnetics

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