A ratiometric fluorescent probe for bioimaging and biosensing of HBrO in mitochondria upon oxidative stress

Hong Huang; Yang Tian

doi:10.1039/C8CC07125J

A ratiometric fluorescent probe for bioimaging and biosensing of HBrO in mitochondria upon oxidative stress

Hong Huang
, Yang Tian^*

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

41 Scopus citations

Abstract

A novel ratiometric fluorescent probe with high selectivity and sensitivity was designed and developed for bioimaging and biosensing of HBrO in mitochondria. Using this useful tool with low cytotoxicity and good biocompatibility, it was found that O₂⁻-induced oxidative stress triggered the burst of HBrO in mitochondria.

Original language	English
Pages (from-to)	12198-12201
Number of pages	4
Journal	Chemical Communications
Volume	54
Issue number	86
DOIs	https://doi.org/10.1039/C8CC07125J
State	Published - 2018

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title = "A ratiometric fluorescent probe for bioimaging and biosensing of HBrO in mitochondria upon oxidative stress",

abstract = "A novel ratiometric fluorescent probe with high selectivity and sensitivity was designed and developed for bioimaging and biosensing of HBrO in mitochondria. Using this useful tool with low cytotoxicity and good biocompatibility, it was found that O2−-induced oxidative stress triggered the burst of HBrO in mitochondria.",

author = "Hong Huang and Yang Tian",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry.",

year = "2018",

doi = "10.1039/C8CC07125J",

language = "英语",

volume = "54",

pages = "12198--12201",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - A ratiometric fluorescent probe for bioimaging and biosensing of HBrO in mitochondria upon oxidative stress

AU - Huang, Hong

AU - Tian, Yang

N1 - Publisher Copyright: © The Royal Society of Chemistry.

PY - 2018

Y1 - 2018

N2 - A novel ratiometric fluorescent probe with high selectivity and sensitivity was designed and developed for bioimaging and biosensing of HBrO in mitochondria. Using this useful tool with low cytotoxicity and good biocompatibility, it was found that O2−-induced oxidative stress triggered the burst of HBrO in mitochondria.

AB - A novel ratiometric fluorescent probe with high selectivity and sensitivity was designed and developed for bioimaging and biosensing of HBrO in mitochondria. Using this useful tool with low cytotoxicity and good biocompatibility, it was found that O2−-induced oxidative stress triggered the burst of HBrO in mitochondria.

UR - https://www.scopus.com/pages/publications/85055613065

U2 - 10.1039/C8CC07125J

DO - 10.1039/C8CC07125J

M3 - 文章

C2 - 30306159

AN - SCOPUS:85055613065

SN - 1359-7345

VL - 54

SP - 12198

EP - 12201

JO - Chemical Communications

JF - Chemical Communications

IS - 86

ER -

A ratiometric fluorescent probe for bioimaging and biosensing of HBrO in mitochondria upon oxidative stress

Abstract

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