A ratiometric fluorescent DNA nanoprobe for cerebral adenosine triphosphate assay

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Abstract

A silver nanocluster-based ratiometric fluorescent nanosensor was developed for the determination of ATP in the cerebrospinal fluid of a mouse brain. Using this useful tool with good stability and high selectivity as well as a wide linear detection range, it was found that the ATP concentration in a mouse brain with Alzheimer's disease was 2300-fold higher than that in a normal one.

Original languageEnglish
Pages (from-to)9955-9958
Number of pages4
JournalChemical Communications
Volume55
Issue number67
DOIs
StatePublished - 2019

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