A ratiometric electrochemical sensor for selectively monitoring monoamine oxidase A in the live brain

Chuanping Zhang; Chenxiao Tang; Yuxiao Mei; Limin Zhang; Anwei Zhu; Yang Tian

doi:10.1039/d1cc00787d

A ratiometric electrochemical sensor for selectively monitoring monoamine oxidase A in the live brain

Chuanping Zhang
, Chenxiao Tang
, Yuxiao Mei
, Limin Zhang
, Anwei Zhu^*
, Yang Tian

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Herein, an electrochemical method for selectively sensing and accurately quantifying monoamine oxidase A (MAO-A) in the cortex and thalamus of a live mouse brain was reported. Using this tool, it was found that MAO-A increased Ca²⁺entry into neuronsviathe TPRM2 channel in the live mouse brain of an AD model.

Original language	English
Pages (from-to)	6487-6490
Number of pages	4
Journal	Chemical Communications
Volume	57
Issue number	53
DOIs	https://doi.org/10.1039/d1cc00787d
State	Published - 7 Jul 2021

Access to Document

10.1039/d1cc00787d

Cite this

@article{1daa2f9397c442feb87976112cb66ae0,

title = "A ratiometric electrochemical sensor for selectively monitoring monoamine oxidase A in the live brain",

abstract = "Herein, an electrochemical method for selectively sensing and accurately quantifying monoamine oxidase A (MAO-A) in the cortex and thalamus of a live mouse brain was reported. Using this tool, it was found that MAO-A increased Ca2+entry into neuronsviathe TPRM2 channel in the live mouse brain of an AD model.",

author = "Chuanping Zhang and Chenxiao Tang and Yuxiao Mei and Limin Zhang and Anwei Zhu and Yang Tian",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2021.",

year = "2021",

month = jul,

day = "7",

doi = "10.1039/d1cc00787d",

language = "英语",

volume = "57",

pages = "6487--6490",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "53",

}

TY - JOUR

T1 - A ratiometric electrochemical sensor for selectively monitoring monoamine oxidase A in the live brain

AU - Zhang, Chuanping

AU - Tang, Chenxiao

AU - Mei, Yuxiao

AU - Zhang, Limin

AU - Zhu, Anwei

AU - Tian, Yang

PY - 2021/7/7

Y1 - 2021/7/7

N2 - Herein, an electrochemical method for selectively sensing and accurately quantifying monoamine oxidase A (MAO-A) in the cortex and thalamus of a live mouse brain was reported. Using this tool, it was found that MAO-A increased Ca2+entry into neuronsviathe TPRM2 channel in the live mouse brain of an AD model.

AB - Herein, an electrochemical method for selectively sensing and accurately quantifying monoamine oxidase A (MAO-A) in the cortex and thalamus of a live mouse brain was reported. Using this tool, it was found that MAO-A increased Ca2+entry into neuronsviathe TPRM2 channel in the live mouse brain of an AD model.

UR - https://www.scopus.com/pages/publications/85109007680

U2 - 10.1039/d1cc00787d

DO - 10.1039/d1cc00787d

M3 - 文章

C2 - 34100043

AN - SCOPUS:85109007680

SN - 1359-7345

VL - 57

SP - 6487

EP - 6490

JO - Chemical Communications

JF - Chemical Communications

IS - 53

ER -

A ratiometric electrochemical sensor for selectively monitoring monoamine oxidase A in the live brain

Abstract

Access to Document

Other files and links

Fingerprint

Cite this