A quartz crystal microbalance-based molecular ruler for biopolymers

  • Hongwei Ma*
  • , Jian'An He
  • , Zhiqiang Zhu
  • , Bei'Er Lv
  • , Di Li
  • , Chunhai Fan
  • , Jing Fang
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

We developed a quartz crystal microbalance (QCM) based molecular ruler that measures the length of surface immobilized, hydrated biopolymers (DNA and proteins). These biopolymers acted as stakes that solidified surrounding liquid at high frequency vibration in QCM measurements, which led to a simple linear frequency-thickness relation.

Original languageEnglish
Pages (from-to)949-951
Number of pages3
JournalChemical Communications
Volume46
Issue number6
DOIs
StatePublished - 2010
Externally publishedYes

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