A practical synthesis of novel chiral sulfoxide-nitrogen ligands

Ming Wang; Jianpeng Wei; Qiaoling Fan; Xuefeng Jiang

doi:10.1016/j.tet.2015.08.004

A practical synthesis of novel chiral sulfoxide-nitrogen ligands

Ming Wang, Jianpeng Wei, Qiaoling Fan, Xuefeng Jiang

School of Chemistry and Molecular Engineering

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Novel chiral sulfoxide-nitrogen ligands which are derived from amino alcohols were developed. All of fourteen sulfoxide-nitrogen ligands can be synthesized by three steps without any chiral auxiliary. In addition, every step of the synthesis can be achieved in gram-scale by using the preparation of L9-L12 as examples. These sulfoxide-nitrogen ligands may be applicable to the asymmetric catalytic 1,3-dipolar cycloaddition of azomethine ylide with alkylidene malonate.

Original language	English
Pages (from-to)	2671-2676
Number of pages	6
Journal	Tetrahedron
Volume	72
Issue number	21
DOIs	https://doi.org/10.1016/j.tet.2015.08.004
State	Published - 26 May 2016

Keywords

Chiral ligands
Gram-scale preparation
Oxidation
Sulfoxide

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10.1016/j.tet.2015.08.004

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title = "A practical synthesis of novel chiral sulfoxide-nitrogen ligands",

abstract = "Novel chiral sulfoxide-nitrogen ligands which are derived from amino alcohols were developed. All of fourteen sulfoxide-nitrogen ligands can be synthesized by three steps without any chiral auxiliary. In addition, every step of the synthesis can be achieved in gram-scale by using the preparation of L9-L12 as examples. These sulfoxide-nitrogen ligands may be applicable to the asymmetric catalytic 1,3-dipolar cycloaddition of azomethine ylide with alkylidene malonate.",

keywords = "Chiral ligands, Gram-scale preparation, Oxidation, Sulfoxide",

author = "Ming Wang and Jianpeng Wei and Qiaoling Fan and Xuefeng Jiang",

year = "2016",

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doi = "10.1016/j.tet.2015.08.004",

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T1 - A practical synthesis of novel chiral sulfoxide-nitrogen ligands

AU - Wang, Ming

AU - Wei, Jianpeng

AU - Fan, Qiaoling

AU - Jiang, Xuefeng

PY - 2016/5/26

Y1 - 2016/5/26

N2 - Novel chiral sulfoxide-nitrogen ligands which are derived from amino alcohols were developed. All of fourteen sulfoxide-nitrogen ligands can be synthesized by three steps without any chiral auxiliary. In addition, every step of the synthesis can be achieved in gram-scale by using the preparation of L9-L12 as examples. These sulfoxide-nitrogen ligands may be applicable to the asymmetric catalytic 1,3-dipolar cycloaddition of azomethine ylide with alkylidene malonate.

AB - Novel chiral sulfoxide-nitrogen ligands which are derived from amino alcohols were developed. All of fourteen sulfoxide-nitrogen ligands can be synthesized by three steps without any chiral auxiliary. In addition, every step of the synthesis can be achieved in gram-scale by using the preparation of L9-L12 as examples. These sulfoxide-nitrogen ligands may be applicable to the asymmetric catalytic 1,3-dipolar cycloaddition of azomethine ylide with alkylidene malonate.

KW - Chiral ligands

KW - Gram-scale preparation

KW - Oxidation

KW - Sulfoxide

UR - https://www.scopus.com/pages/publications/84940061518

U2 - 10.1016/j.tet.2015.08.004

DO - 10.1016/j.tet.2015.08.004

M3 - 文章

AN - SCOPUS:84940061518

SN - 0040-4020

VL - 72

SP - 2671

EP - 2676

JO - Tetrahedron

JF - Tetrahedron

IS - 21

ER -

A practical synthesis of novel chiral sulfoxide-nitrogen ligands

Abstract

Keywords

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