A Practical Synthesis of Near-Infrared Benzannulated Xanthenoid Dyes

  • Jin Li
  • , Ruwei Wei
  • , Xiaodong Zhang
  • , Xiao Luo
  • , Xuhong Qian
  • , Youjun Yang*
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Near-infrared dyes are sought after for their potential in biomedical applications. Benzoxanthene dyes with a non-oxygen bridging atom are expected to exhibit longer absorption and emission wavelengths than their oxygen-containing counterparts, yet their synthesis remains unaddressed. Herein, we report the first syntheses of non-oxygen- bridged benzoxanthenes starting from a 7-bromo-2-aminonaphthalene derivative, and discuss their photophysical properties as well as their potential for in vivo imaging.

Original languageEnglish
Pages (from-to)101-108
Number of pages8
JournalSynlett
Volume35
Issue number1
DOIs
StatePublished - 31 Mar 2023

Keywords

  • benzoxanthene
  • fluorescence
  • near-infrared
  • stability
  • synthesis

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