A practical synthesis of 2-amino-5-methoxylpropiophenone

Shan Bao Yu; Li Juan Zhang; Yu Luo; Wei Lu

doi:10.1016/j.cclet.2010.07.033

A practical synthesis of 2-amino-5-methoxylpropiophenone

Shan Bao Yu, Li Juan Zhang, Yu Luo, Wei Lu

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

This paper described a practical five-step synthetic approach for 2-amino-5-methoxylpropiophenone in 45% overall yield, using 3- chloropropiophenone as the starting material. The advantages of this procedure include short reaction steps, simple operation and good yield.

Original language	English
Pages (from-to)	1-4
Number of pages	4
Journal	Chinese Chemical Letters
Volume	22
Issue number	1
DOIs	https://doi.org/10.1016/j.cclet.2010.07.033
State	Published - Jan 2011

Keywords

Camptothecin
SN38
Synthesis

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10.1016/j.cclet.2010.07.033

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title = "A practical synthesis of 2-amino-5-methoxylpropiophenone",

abstract = "This paper described a practical five-step synthetic approach for 2-amino-5-methoxylpropiophenone in 45\% overall yield, using 3- chloropropiophenone as the starting material. The advantages of this procedure include short reaction steps, simple operation and good yield.",

keywords = "Camptothecin, SN38, Synthesis",

author = "Yu, \{Shan Bao\} and Zhang, \{Li Juan\} and Yu Luo and Wei Lu",

year = "2011",

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doi = "10.1016/j.cclet.2010.07.033",

language = "英语",

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AU - Yu, Shan Bao

AU - Zhang, Li Juan

AU - Luo, Yu

AU - Lu, Wei

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N2 - This paper described a practical five-step synthetic approach for 2-amino-5-methoxylpropiophenone in 45% overall yield, using 3- chloropropiophenone as the starting material. The advantages of this procedure include short reaction steps, simple operation and good yield.

AB - This paper described a practical five-step synthetic approach for 2-amino-5-methoxylpropiophenone in 45% overall yield, using 3- chloropropiophenone as the starting material. The advantages of this procedure include short reaction steps, simple operation and good yield.

KW - Camptothecin

KW - SN38

KW - Synthesis

UR - https://www.scopus.com/pages/publications/78650297009

U2 - 10.1016/j.cclet.2010.07.033

DO - 10.1016/j.cclet.2010.07.033

M3 - 文章

AN - SCOPUS:78650297009

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SP - 1

EP - 4

JO - Chinese Chemical Letters

JF - Chinese Chemical Letters

IS - 1

ER -

A practical synthesis of 2-amino-5-methoxylpropiophenone

Abstract

Keywords

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