A novel L-lactate sensor based on enzyme electrode modified with ZnO nanoparticles and multiwall carbon nanotubes

Y. T. Wang; L. Yu; J. Wang; L. Lou; W. J. Du; Z. Q. Zhu; H. Peng; J. Z. Zhu

doi:10.1016/j.jelechem.2011.06.024

A novel L-lactate sensor based on enzyme electrode modified with ZnO nanoparticles and multiwall carbon nanotubes

Y. T. Wang, L. Yu, J. Wang, L. Lou, W. J. Du, Z. Q. Zhu, H. Peng, J. Z. Zhu

School of Physics and Electronic Science

East China Normal University

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

A highly sensitive and stable L-lactate sensor based on the synergic action of multi-wall carbon nanotube (MWCNTs) and ZnO nanoparticles has been developed. The unique sandwich-like layer structure (PDDA/LOD/ZnO/MWCNTs) provides a favorable microenvironment to keep the bioactivity of LOD and prevent enzyme molecule leakage. Therefore, the proposed l-lactate biosensor exhibited good analytical performances including high sensitivity and selectivity with satisfactory stability to amperometric determination of l-lactate. The results indicated that the proposed PDDA/LOD/ZnO/MWCNTs film was an attractive matrix for the immobilization of LOD enzymes to fabricate biosensors.

Original language	English
Pages (from-to)	8-12
Number of pages	5
Journal	Journal of Electroanalytical Chemistry
Volume	661
Issue number	1
DOIs	https://doi.org/10.1016/j.jelechem.2011.06.024
State	Published - 1 Oct 2011

Keywords

Biosensors
CNTs
Electrochemical method
L-Lactate
ZnO nanoparticles

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10.1016/j.jelechem.2011.06.024

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title = "A novel L-lactate sensor based on enzyme electrode modified with ZnO nanoparticles and multiwall carbon nanotubes",

abstract = "A highly sensitive and stable L-lactate sensor based on the synergic action of multi-wall carbon nanotube (MWCNTs) and ZnO nanoparticles has been developed. The unique sandwich-like layer structure (PDDA/LOD/ZnO/MWCNTs) provides a favorable microenvironment to keep the bioactivity of LOD and prevent enzyme molecule leakage. Therefore, the proposed l-lactate biosensor exhibited good analytical performances including high sensitivity and selectivity with satisfactory stability to amperometric determination of l-lactate. The results indicated that the proposed PDDA/LOD/ZnO/MWCNTs film was an attractive matrix for the immobilization of LOD enzymes to fabricate biosensors.",

keywords = "Biosensors, CNTs, Electrochemical method, L-Lactate, ZnO nanoparticles",

author = "Wang, \{Y. T.\} and L. Yu and J. Wang and L. Lou and Du, \{W. J.\} and Zhu, \{Z. Q.\} and H. Peng and Zhu, \{J. Z.\}",

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T1 - A novel L-lactate sensor based on enzyme electrode modified with ZnO nanoparticles and multiwall carbon nanotubes

AU - Wang, Y. T.

AU - Yu, L.

AU - Wang, J.

AU - Lou, L.

AU - Du, W. J.

AU - Zhu, Z. Q.

AU - Peng, H.

AU - Zhu, J. Z.

PY - 2011/10/1

Y1 - 2011/10/1

N2 - A highly sensitive and stable L-lactate sensor based on the synergic action of multi-wall carbon nanotube (MWCNTs) and ZnO nanoparticles has been developed. The unique sandwich-like layer structure (PDDA/LOD/ZnO/MWCNTs) provides a favorable microenvironment to keep the bioactivity of LOD and prevent enzyme molecule leakage. Therefore, the proposed l-lactate biosensor exhibited good analytical performances including high sensitivity and selectivity with satisfactory stability to amperometric determination of l-lactate. The results indicated that the proposed PDDA/LOD/ZnO/MWCNTs film was an attractive matrix for the immobilization of LOD enzymes to fabricate biosensors.

AB - A highly sensitive and stable L-lactate sensor based on the synergic action of multi-wall carbon nanotube (MWCNTs) and ZnO nanoparticles has been developed. The unique sandwich-like layer structure (PDDA/LOD/ZnO/MWCNTs) provides a favorable microenvironment to keep the bioactivity of LOD and prevent enzyme molecule leakage. Therefore, the proposed l-lactate biosensor exhibited good analytical performances including high sensitivity and selectivity with satisfactory stability to amperometric determination of l-lactate. The results indicated that the proposed PDDA/LOD/ZnO/MWCNTs film was an attractive matrix for the immobilization of LOD enzymes to fabricate biosensors.

KW - Biosensors

KW - CNTs

KW - Electrochemical method

KW - L-Lactate

KW - ZnO nanoparticles

UR - https://www.scopus.com/pages/publications/80053338504

U2 - 10.1016/j.jelechem.2011.06.024

DO - 10.1016/j.jelechem.2011.06.024

M3 - 文章

AN - SCOPUS:80053338504

SN - 1572-6657

VL - 661

SP - 8

EP - 12

JO - Journal of Electroanalytical Chemistry

JF - Journal of Electroanalytical Chemistry

IS - 1

ER -

A novel L-lactate sensor based on enzyme electrode modified with ZnO nanoparticles and multiwall carbon nanotubes

Abstract

Keywords

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