A novel glucose biosensor based on palladium nanoparticles and its application in detection of glucose level in urine

Fen Fen Zhang; Qiao Wan; Chen Xin Li; Zi Qiang Zhu; Yue Zhong Xian; Li Tong Jin; Katsunobu Yamamoto

doi:10.1002/cjoc.20030211219

A novel glucose biosensor based on palladium nanoparticles and its application in detection of glucose level in urine

Fen Fen Zhang^*
, Qiao Wan
, Chen Xin Li
, Zi Qiang Zhu
, Yue Zhong Xian
, Li Tong Jin
, Katsunobu Yamamoto

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

A novel glucose biosensor was constructed by electrodcposition of highly dispersed palladium (Pd) nanoparticles on a glassy carbon electrode (GCE). Atomic force microscopy (AFM) was applied to characterize its surface morphology. Electrodeposited Pd nanoparticles exhibited efficiently electrocatalytic oxidation for hydrogen peroxide (H₂O₂) with relatively high sensitivity and stability, which was studied by CV technique and Raman spectroscopy, respectively. The GC/Pd/GOD/Nafion system allowed a low working potential of + 0.3 V (vs. SCE). Its signal current was linearly related to the glucose concentration in the range of 1.0 × 10^-6-1.2 × 10^-4 mol·L^-1 with a detection limit of 5.0 × 10^-7 mol·L^-1. The sensor required no special pretreatment to suppress interference from urate and L-ascorbate. It was successfully used in detection of glucose level in human urine with high stability, sensitivity and anti-poisoning ability.

Original language	English
Pages (from-to)	1619-1623
Number of pages	5
Journal	Chinese Journal of Chemistry
Volume	21
Issue number	12
DOIs	https://doi.org/10.1002/cjoc.20030211219
State	Published - 2003

Keywords

Electrocatalyze
Glucose oxidase
Hydrogen peroxide
Palladium nanoparticle

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title = "A novel glucose biosensor based on palladium nanoparticles and its application in detection of glucose level in urine",

abstract = "A novel glucose biosensor was constructed by electrodcposition of highly dispersed palladium (Pd) nanoparticles on a glassy carbon electrode (GCE). Atomic force microscopy (AFM) was applied to characterize its surface morphology. Electrodeposited Pd nanoparticles exhibited efficiently electrocatalytic oxidation for hydrogen peroxide (H2O2) with relatively high sensitivity and stability, which was studied by CV technique and Raman spectroscopy, respectively. The GC/Pd/GOD/Nafion system allowed a low working potential of + 0.3 V (vs. SCE). Its signal current was linearly related to the glucose concentration in the range of 1.0 × 10-6-1.2 × 10-4 mol·L-1 with a detection limit of 5.0 × 10-7 mol·L-1. The sensor required no special pretreatment to suppress interference from urate and L-ascorbate. It was successfully used in detection of glucose level in human urine with high stability, sensitivity and anti-poisoning ability.",

keywords = "Electrocatalyze, Glucose oxidase, Hydrogen peroxide, Palladium nanoparticle",

author = "Zhang, \{Fen Fen\} and Qiao Wan and Li, \{Chen Xin\} and Zhu, \{Zi Qiang\} and Xian, \{Yue Zhong\} and Jin, \{Li Tong\} and Katsunobu Yamamoto",

year = "2003",

doi = "10.1002/cjoc.20030211219",

language = "英语",

volume = "21",

pages = "1619--1623",

journal = "Chinese Journal of Chemistry",

issn = "1001-604X",

publisher = "John Wiley and Sons Inc",

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TY - JOUR

T1 - A novel glucose biosensor based on palladium nanoparticles and its application in detection of glucose level in urine

AU - Zhang, Fen Fen

AU - Wan, Qiao

AU - Li, Chen Xin

AU - Zhu, Zi Qiang

AU - Xian, Yue Zhong

AU - Jin, Li Tong

AU - Yamamoto, Katsunobu

PY - 2003

Y1 - 2003

N2 - A novel glucose biosensor was constructed by electrodcposition of highly dispersed palladium (Pd) nanoparticles on a glassy carbon electrode (GCE). Atomic force microscopy (AFM) was applied to characterize its surface morphology. Electrodeposited Pd nanoparticles exhibited efficiently electrocatalytic oxidation for hydrogen peroxide (H2O2) with relatively high sensitivity and stability, which was studied by CV technique and Raman spectroscopy, respectively. The GC/Pd/GOD/Nafion system allowed a low working potential of + 0.3 V (vs. SCE). Its signal current was linearly related to the glucose concentration in the range of 1.0 × 10-6-1.2 × 10-4 mol·L-1 with a detection limit of 5.0 × 10-7 mol·L-1. The sensor required no special pretreatment to suppress interference from urate and L-ascorbate. It was successfully used in detection of glucose level in human urine with high stability, sensitivity and anti-poisoning ability.

AB - A novel glucose biosensor was constructed by electrodcposition of highly dispersed palladium (Pd) nanoparticles on a glassy carbon electrode (GCE). Atomic force microscopy (AFM) was applied to characterize its surface morphology. Electrodeposited Pd nanoparticles exhibited efficiently electrocatalytic oxidation for hydrogen peroxide (H2O2) with relatively high sensitivity and stability, which was studied by CV technique and Raman spectroscopy, respectively. The GC/Pd/GOD/Nafion system allowed a low working potential of + 0.3 V (vs. SCE). Its signal current was linearly related to the glucose concentration in the range of 1.0 × 10-6-1.2 × 10-4 mol·L-1 with a detection limit of 5.0 × 10-7 mol·L-1. The sensor required no special pretreatment to suppress interference from urate and L-ascorbate. It was successfully used in detection of glucose level in human urine with high stability, sensitivity and anti-poisoning ability.

KW - Electrocatalyze

KW - Glucose oxidase

KW - Hydrogen peroxide

KW - Palladium nanoparticle

UR - https://www.scopus.com/pages/publications/20044378225

U2 - 10.1002/cjoc.20030211219

DO - 10.1002/cjoc.20030211219

M3 - 文章

AN - SCOPUS:20044378225

SN - 1001-604X

VL - 21

SP - 1619

EP - 1623

JO - Chinese Journal of Chemistry

JF - Chinese Journal of Chemistry

IS - 12

ER -

A novel glucose biosensor based on palladium nanoparticles and its application in detection of glucose level in urine

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Keywords

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