TY - JOUR
T1 - A nanosized metal–organic framework for visual detection of fluoride ions with smartphone via colorimetric test kit
AU - Hou, Dongyan
AU - You, Yi
AU - Wu, Xiaohong
AU - Li, Chen
AU - Wu, Shan
AU - Zhang, Cuiling
AU - Xian, Yuezhong
N1 - Publisher Copyright:
© 2021 Elsevier B.V.
PY - 2021/4/1
Y1 - 2021/4/1
N2 - Fluoride ion (F−) is an essential micronutrient in the human body, however, an abnormal large intake of F− can result in adverse effects, such as skeletal fluorosis or DNA damage. Therefore, it is of great significance to develop convenient assays for the visual detection of F− with high sensitivity. We rationally developed the nanosized iron-based metal organic frameworks (Fe-MOFs) by using 3,5-dicarboxybenzeneboronic acid as organic linkers and Fe3+ as metal ions through the solvothermal method, which can be applied for detecting F− with high sensitivity and selectivity owing to the specific recognition of boronic acid groups towards F− and the strong binding affinity between F− and Fe3+. The Fe-MOFs possess excellent peroxidase-like activity, which can be effectively inhibited by F−. Moreover, a portable test kit for the determination of F− was developed by embedding Fe-MOFs into hydrogel, and the visual measurement of F− was realized based on smartphone by identifying the color signal of the oxidation of 3,3',5,5'-tetramethylbenzidine dihydrochloride. The output signal (R/G) was linear with F− concentration in the range of 10.0–200.0 μM. The Fe-MOFs-based colorimetric strategy is easy-operation, low-cost and equipment-free, which has been further applied to detect F− in the real water samples.
AB - Fluoride ion (F−) is an essential micronutrient in the human body, however, an abnormal large intake of F− can result in adverse effects, such as skeletal fluorosis or DNA damage. Therefore, it is of great significance to develop convenient assays for the visual detection of F− with high sensitivity. We rationally developed the nanosized iron-based metal organic frameworks (Fe-MOFs) by using 3,5-dicarboxybenzeneboronic acid as organic linkers and Fe3+ as metal ions through the solvothermal method, which can be applied for detecting F− with high sensitivity and selectivity owing to the specific recognition of boronic acid groups towards F− and the strong binding affinity between F− and Fe3+. The Fe-MOFs possess excellent peroxidase-like activity, which can be effectively inhibited by F−. Moreover, a portable test kit for the determination of F− was developed by embedding Fe-MOFs into hydrogel, and the visual measurement of F− was realized based on smartphone by identifying the color signal of the oxidation of 3,3',5,5'-tetramethylbenzidine dihydrochloride. The output signal (R/G) was linear with F− concentration in the range of 10.0–200.0 μM. The Fe-MOFs-based colorimetric strategy is easy-operation, low-cost and equipment-free, which has been further applied to detect F− in the real water samples.
KW - Colorimetric detection
KW - Fluoride ions
KW - Metal organic frameworks
KW - Peroxidase mimics
KW - Smartphone-assisted measurement
UR - https://www.scopus.com/pages/publications/85100047225
U2 - 10.1016/j.snb.2021.129508
DO - 10.1016/j.snb.2021.129508
M3 - 文章
AN - SCOPUS:85100047225
SN - 0925-4005
VL - 332
JO - Sensors and Actuators B: Chemical
JF - Sensors and Actuators B: Chemical
M1 - 129508
ER -