A multi-calibration potentiometric sensing array based on diboronic acid-PtAu/CNTs nanozyme for home monitoring of urine glucose

Fan Wang, Jinhuan Zhang, Mengdi Zhang, Cuiyue Xu, Shengqi Cheng, Qingjiang Wang, Fan Zhang*, Xiao He*, Pingang He

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

All-solid-state potentiometric sensors that are easily miniaturized and arrayed are widely used in home diagnostics. However, changes in sample matrix compositions tend to affect the basic potential of the potentiometric sensor, and pH of sample could change the response slope, thus affecting the detection reliability. This study takes the detection of glucose in urine as a model to increase the reliability of potentiometric sensors in home detection. PtAu/CNTs nanozyme modified by diboronic acid has been designed, showing better catalytic selectivity for glucose by experiments and theoretical calculations. Moreover, glucose electrode group in a multi-calibration glucose potentiometric sensing array can realize the basic potential calibration of sensing channel by the calibration channel. Meanwhile, the pH electrode group can not only measure the urine pH, but also calibrate the response slope of the glucose electrode group, thus improving the reliability of home detection.

Original languageEnglish
Article number340598
JournalAnalytica Chimica Acta
Volume1237
DOIs
StatePublished - 2 Jan 2023

Keywords

  • Diboronic acid-PtAu/CNTs nanozyme
  • Home detection
  • Multi-calibration
  • Potentiometric sensing array
  • Urine glucose

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