A metal–organic framework composite loaded with coumarin guests as a turn-on luminescent sensor for detection of cysteine in aqueous solution

Xi Xi Wang; Rui Peng Liu; Ai Ling Cheng; Qing Song Xue; En Qing Gao

doi:10.1016/j.poly.2024.117190

A metal–organic framework composite loaded with coumarin guests as a turn-on luminescent sensor for detection of cysteine in aqueous solution

Xi Xi Wang
, Rui Peng Liu
, Ai Ling Cheng^*
, Qing Song Xue
, En Qing Gao

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

Abstract

In this work, a composite material (ACE@UiO-66-NH₂) has been synthesized conveniently by loading a cysteine-responsive molecular probe Acrylic acid 3-acetyl-2-oxo-2H-chromen-7-yl ester (ACE) on a UiO-type zirconium-based metal–organic framework (UiO-66-NH₂). Furthermore, the resulting ACE@UiO-66-NH₂ demonstrated to be a fluorescent turn-on probe for selective recognition of Cys from other amino acids in aqueous HEPES buffer systems. Additionally, the proposed recognition mechanism has been confirmed by ¹H NMR and TLC. The study provided a promising approach to rationally design MOF-based fluorescent sensor for Cys in aqueous system.

Original language	English
Article number	117190
Journal	Polyhedron
Volume	263
DOIs	https://doi.org/10.1016/j.poly.2024.117190
State	Published - 15 Nov 2024

Keywords

Aqueous
Coumarin
Cysteine
Luminescent sensor
Zr-MOF

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10.1016/j.poly.2024.117190

Cite this

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title = "A metal–organic framework composite loaded with coumarin guests as a turn-on luminescent sensor for detection of cysteine in aqueous solution",

abstract = "In this work, a composite material (ACE@UiO-66-NH2) has been synthesized conveniently by loading a cysteine-responsive molecular probe Acrylic acid 3-acetyl-2-oxo-2H-chromen-7-yl ester (ACE) on a UiO-type zirconium-based metal–organic framework (UiO-66-NH2). Furthermore, the resulting ACE@UiO-66-NH2 demonstrated to be a fluorescent turn-on probe for selective recognition of Cys from other amino acids in aqueous HEPES buffer systems. Additionally, the proposed recognition mechanism has been confirmed by 1H NMR and TLC. The study provided a promising approach to rationally design MOF-based fluorescent sensor for Cys in aqueous system.",

keywords = "Aqueous, Coumarin, Cysteine, Luminescent sensor, Zr-MOF",

author = "Wang, \{Xi Xi\} and Liu, \{Rui Peng\} and Cheng, \{Ai Ling\} and Xue, \{Qing Song\} and Gao, \{En Qing\}",

note = "Publisher Copyright: {\textcopyright} 2024 Elsevier Ltd",

year = "2024",

month = nov,

day = "15",

doi = "10.1016/j.poly.2024.117190",

language = "英语",

volume = "263",

journal = "Polyhedron",

issn = "0277-5387",

publisher = "Elsevier Ltd",

}

TY - JOUR

T1 - A metal–organic framework composite loaded with coumarin guests as a turn-on luminescent sensor for detection of cysteine in aqueous solution

AU - Wang, Xi Xi

AU - Liu, Rui Peng

AU - Cheng, Ai Ling

AU - Xue, Qing Song

AU - Gao, En Qing

PY - 2024/11/15

Y1 - 2024/11/15

N2 - In this work, a composite material (ACE@UiO-66-NH2) has been synthesized conveniently by loading a cysteine-responsive molecular probe Acrylic acid 3-acetyl-2-oxo-2H-chromen-7-yl ester (ACE) on a UiO-type zirconium-based metal–organic framework (UiO-66-NH2). Furthermore, the resulting ACE@UiO-66-NH2 demonstrated to be a fluorescent turn-on probe for selective recognition of Cys from other amino acids in aqueous HEPES buffer systems. Additionally, the proposed recognition mechanism has been confirmed by 1H NMR and TLC. The study provided a promising approach to rationally design MOF-based fluorescent sensor for Cys in aqueous system.

AB - In this work, a composite material (ACE@UiO-66-NH2) has been synthesized conveniently by loading a cysteine-responsive molecular probe Acrylic acid 3-acetyl-2-oxo-2H-chromen-7-yl ester (ACE) on a UiO-type zirconium-based metal–organic framework (UiO-66-NH2). Furthermore, the resulting ACE@UiO-66-NH2 demonstrated to be a fluorescent turn-on probe for selective recognition of Cys from other amino acids in aqueous HEPES buffer systems. Additionally, the proposed recognition mechanism has been confirmed by 1H NMR and TLC. The study provided a promising approach to rationally design MOF-based fluorescent sensor for Cys in aqueous system.

KW - Aqueous

KW - Coumarin

KW - Cysteine

KW - Luminescent sensor

KW - Zr-MOF

UR - https://www.scopus.com/pages/publications/85202969776

U2 - 10.1016/j.poly.2024.117190

DO - 10.1016/j.poly.2024.117190

M3 - 文章

AN - SCOPUS:85202969776

SN - 0277-5387

VL - 263

JO - Polyhedron

JF - Polyhedron

M1 - 117190

ER -

A metal–organic framework composite loaded with coumarin guests as a turn-on luminescent sensor for detection of cysteine in aqueous solution

Abstract

Keywords

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