A highly sensitive and selective hypochlorite fluorescent probe based on oxidation of hydrazine via free radical mechanism

Tanyu Cheng; Junwei Zhao; Ziyun Wang; Juzeng An; Yufang Xu; Xuhong Qian; Guohua Liu

doi:10.1016/j.dyepig.2015.10.020

A highly sensitive and selective hypochlorite fluorescent probe based on oxidation of hydrazine via free radical mechanism

Tanyu Cheng
, Junwei Zhao
, Ziyun Wang
, Juzeng An
, Yufang Xu^*
, Xuhong Qian
, Guohua Liu

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

50 Scopus citations

Abstract

Developing fluorescent probes for selective and sensitive detection of hypochlorite has received much attention, because hypochlorite is closely related to human health. In this work, a new fluorescent probe based on dipyrromethene boron difluoride (BODIPY) fluorophore using hydrazine as detecting group for hypochlorite was synthesized and fully characterized. The reaction of the probe with sodium hypochlorite is complete within 1 min in phosphate-buffered saline, and the fluorescence of the system significantly enhanced. The probe also exhibits admirable sensitivity and selectivity as well. The results of nuclear magnetic resonance monitoring and high-performance liquid chromatography analysis indicate that the detection process plausibly involves a free radical oxidation mechanism.

Original language	English
Pages (from-to)	218-223
Number of pages	6
Journal	Dyes and Pigments
Volume	126
DOIs	https://doi.org/10.1016/j.dyepig.2015.10.020
State	Published - 1 Mar 2016
Externally published	Yes

Keywords

BODIPY
Fluorescent probe
Hydrazine
Hypochlorite
Off-on
Oxidation

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.dyepig.2015.10.020

Cite this

@article{266013b745a34ac0bb2de9590ba128f8,

title = "A highly sensitive and selective hypochlorite fluorescent probe based on oxidation of hydrazine via free radical mechanism",

abstract = "Developing fluorescent probes for selective and sensitive detection of hypochlorite has received much attention, because hypochlorite is closely related to human health. In this work, a new fluorescent probe based on dipyrromethene boron difluoride (BODIPY) fluorophore using hydrazine as detecting group for hypochlorite was synthesized and fully characterized. The reaction of the probe with sodium hypochlorite is complete within 1 min in phosphate-buffered saline, and the fluorescence of the system significantly enhanced. The probe also exhibits admirable sensitivity and selectivity as well. The results of nuclear magnetic resonance monitoring and high-performance liquid chromatography analysis indicate that the detection process plausibly involves a free radical oxidation mechanism.",

keywords = "BODIPY, Fluorescent probe, Hydrazine, Hypochlorite, Off-on, Oxidation",

author = "Tanyu Cheng and Junwei Zhao and Ziyun Wang and Juzeng An and Yufang Xu and Xuhong Qian and Guohua Liu",

year = "2016",

month = mar,

day = "1",

doi = "10.1016/j.dyepig.2015.10.020",

language = "英语",

volume = "126",

pages = "218--223",

journal = "Dyes and Pigments",

issn = "0143-7208",

publisher = "Elsevier B.V.",

}

TY - JOUR

T1 - A highly sensitive and selective hypochlorite fluorescent probe based on oxidation of hydrazine via free radical mechanism

AU - Cheng, Tanyu

AU - Zhao, Junwei

AU - Wang, Ziyun

AU - An, Juzeng

AU - Xu, Yufang

AU - Qian, Xuhong

AU - Liu, Guohua

PY - 2016/3/1

Y1 - 2016/3/1

N2 - Developing fluorescent probes for selective and sensitive detection of hypochlorite has received much attention, because hypochlorite is closely related to human health. In this work, a new fluorescent probe based on dipyrromethene boron difluoride (BODIPY) fluorophore using hydrazine as detecting group for hypochlorite was synthesized and fully characterized. The reaction of the probe with sodium hypochlorite is complete within 1 min in phosphate-buffered saline, and the fluorescence of the system significantly enhanced. The probe also exhibits admirable sensitivity and selectivity as well. The results of nuclear magnetic resonance monitoring and high-performance liquid chromatography analysis indicate that the detection process plausibly involves a free radical oxidation mechanism.

AB - Developing fluorescent probes for selective and sensitive detection of hypochlorite has received much attention, because hypochlorite is closely related to human health. In this work, a new fluorescent probe based on dipyrromethene boron difluoride (BODIPY) fluorophore using hydrazine as detecting group for hypochlorite was synthesized and fully characterized. The reaction of the probe with sodium hypochlorite is complete within 1 min in phosphate-buffered saline, and the fluorescence of the system significantly enhanced. The probe also exhibits admirable sensitivity and selectivity as well. The results of nuclear magnetic resonance monitoring and high-performance liquid chromatography analysis indicate that the detection process plausibly involves a free radical oxidation mechanism.

KW - BODIPY

KW - Fluorescent probe

KW - Hydrazine

KW - Hypochlorite

KW - Off-on

KW - Oxidation

UR - https://www.scopus.com/pages/publications/84955513429

U2 - 10.1016/j.dyepig.2015.10.020

DO - 10.1016/j.dyepig.2015.10.020

M3 - 文章

AN - SCOPUS:84955513429

SN - 0143-7208

VL - 126

SP - 218

EP - 223

JO - Dyes and Pigments

JF - Dyes and Pigments

ER -

A highly sensitive and selective hypochlorite fluorescent probe based on oxidation of hydrazine via free radical mechanism

Abstract

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this