A highly selective fluorescent probe for fast detection of hydrogen sulfide in aqueous solution and living cells

Zheng Xu; Lin Xu; Ji Zhou; Yufang Xu; Weiping Zhu; Xuhong Qian

doi:10.1039/c2cc36141h

A highly selective fluorescent probe for fast detection of hydrogen sulfide in aqueous solution and living cells

Zheng Xu
, Lin Xu
, Ji Zhou
, Yufang Xu
, Weiping Zhu
, Xuhong Qian^*

^*Corresponding author for this work

East China University of Science and Technology

Research output: Contribution to journal › Article › peer-review

239 Scopus citations

Abstract

A new ratiometric fluorescence probe E1 based on an excited-state intramolecular proton transfer (ESIPT) mechanism for detection of hydrogen sulfide (H₂S) is reported. E1 responds to H₂S quickly and showed a 30-fold fluorescence enhancement in 2 minutes. Moreover, E1 can detect H₂S quantitatively with a detection limit as low as 0.12 μM in aqueous solution. Its potential for biological applications was confirmed by employing it for fluorescence imaging of H₂S in living cells.

Original language	English
Pages (from-to)	10871-10873
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	88
DOIs	https://doi.org/10.1039/c2cc36141h
State	Published - 10 Oct 2012
Externally published	Yes

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title = "A highly selective fluorescent probe for fast detection of hydrogen sulfide in aqueous solution and living cells",

abstract = "A new ratiometric fluorescence probe E1 based on an excited-state intramolecular proton transfer (ESIPT) mechanism for detection of hydrogen sulfide (H2S) is reported. E1 responds to H2S quickly and showed a 30-fold fluorescence enhancement in 2 minutes. Moreover, E1 can detect H2S quantitatively with a detection limit as low as 0.12 μM in aqueous solution. Its potential for biological applications was confirmed by employing it for fluorescence imaging of H2S in living cells.",

author = "Zheng Xu and Lin Xu and Ji Zhou and Yufang Xu and Weiping Zhu and Xuhong Qian",

year = "2012",

month = oct,

day = "10",

doi = "10.1039/c2cc36141h",

language = "英语",

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journal = "Chemical Communications",

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T1 - A highly selective fluorescent probe for fast detection of hydrogen sulfide in aqueous solution and living cells

AU - Xu, Zheng

AU - Xu, Lin

AU - Zhou, Ji

AU - Xu, Yufang

AU - Zhu, Weiping

AU - Qian, Xuhong

PY - 2012/10/10

Y1 - 2012/10/10

N2 - A new ratiometric fluorescence probe E1 based on an excited-state intramolecular proton transfer (ESIPT) mechanism for detection of hydrogen sulfide (H2S) is reported. E1 responds to H2S quickly and showed a 30-fold fluorescence enhancement in 2 minutes. Moreover, E1 can detect H2S quantitatively with a detection limit as low as 0.12 μM in aqueous solution. Its potential for biological applications was confirmed by employing it for fluorescence imaging of H2S in living cells.

AB - A new ratiometric fluorescence probe E1 based on an excited-state intramolecular proton transfer (ESIPT) mechanism for detection of hydrogen sulfide (H2S) is reported. E1 responds to H2S quickly and showed a 30-fold fluorescence enhancement in 2 minutes. Moreover, E1 can detect H2S quantitatively with a detection limit as low as 0.12 μM in aqueous solution. Its potential for biological applications was confirmed by employing it for fluorescence imaging of H2S in living cells.

UR - https://www.scopus.com/pages/publications/84867373631

U2 - 10.1039/c2cc36141h

DO - 10.1039/c2cc36141h

M3 - 文章

C2 - 23023578

AN - SCOPUS:84867373631

SN - 1359-7345

VL - 48

SP - 10871

EP - 10873

JO - Chemical Communications

JF - Chemical Communications

IS - 88

ER -

A highly selective fluorescent probe for fast detection of hydrogen sulfide in aqueous solution and living cells

Abstract

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