A highly selective and sensitive fluorescence "turn-on" probe for Ag + in aqueous solution and live cells

Lin Xu; Yufang Xu; Weiping Zhu; Chunmei Yang; Le Han; Xuhong Qian

doi:10.1039/c2dt30404j

A highly selective and sensitive fluorescence "turn-on" probe for Ag ⁺ in aqueous solution and live cells

Lin Xu
, Yufang Xu
, Weiping Zhu
, Chunmei Yang
, Le Han
, Xuhong Qian^*

^*Corresponding author for this work

East China University of Science and Technology

Research output: Contribution to journal › Article › peer-review

90 Scopus citations

Abstract

A naphthalimide-based fluorescent probe, NPQ, that contains a novel receptor was successfully developed. NPQ exhibited "turn-on" fluorescence and excellent selectivity toward Ag ⁺ in the presence of various other metal ions in aqueous solution. A series of control compounds were designed and synthesized in order to explore the photoinduced electron transfer (PET) quenching mechanism of NPQ and binding mode of NPQ with Ag ⁺. Moreover, with the NPQ-Ag ⁺ complex, I ^- was easily selectively recognized by a marked fluorescence quenching. The live cell imaging experiments demonstrate that NPQ can be used as a fluorescent probe for monitoring Ag ⁺ in living cells.

Original language	English
Pages (from-to)	7212-7217
Number of pages	6
Journal	Dalton Transactions
Volume	41
Issue number	24
DOIs	https://doi.org/10.1039/c2dt30404j
State	Published - 28 Jun 2012
Externally published	Yes

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title = "A highly selective and sensitive fluorescence {"}turn-on{"} probe for Ag + in aqueous solution and live cells",

abstract = "A naphthalimide-based fluorescent probe, NPQ, that contains a novel receptor was successfully developed. NPQ exhibited {"}turn-on{"} fluorescence and excellent selectivity toward Ag + in the presence of various other metal ions in aqueous solution. A series of control compounds were designed and synthesized in order to explore the photoinduced electron transfer (PET) quenching mechanism of NPQ and binding mode of NPQ with Ag +. Moreover, with the NPQ-Ag + complex, I - was easily selectively recognized by a marked fluorescence quenching. The live cell imaging experiments demonstrate that NPQ can be used as a fluorescent probe for monitoring Ag + in living cells.",

author = "Lin Xu and Yufang Xu and Weiping Zhu and Chunmei Yang and Le Han and Xuhong Qian",

year = "2012",

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doi = "10.1039/c2dt30404j",

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T1 - A highly selective and sensitive fluorescence "turn-on" probe for Ag + in aqueous solution and live cells

AU - Xu, Lin

AU - Xu, Yufang

AU - Zhu, Weiping

AU - Yang, Chunmei

AU - Han, Le

AU - Qian, Xuhong

PY - 2012/6/28

Y1 - 2012/6/28

N2 - A naphthalimide-based fluorescent probe, NPQ, that contains a novel receptor was successfully developed. NPQ exhibited "turn-on" fluorescence and excellent selectivity toward Ag + in the presence of various other metal ions in aqueous solution. A series of control compounds were designed and synthesized in order to explore the photoinduced electron transfer (PET) quenching mechanism of NPQ and binding mode of NPQ with Ag +. Moreover, with the NPQ-Ag + complex, I - was easily selectively recognized by a marked fluorescence quenching. The live cell imaging experiments demonstrate that NPQ can be used as a fluorescent probe for monitoring Ag + in living cells.

AB - A naphthalimide-based fluorescent probe, NPQ, that contains a novel receptor was successfully developed. NPQ exhibited "turn-on" fluorescence and excellent selectivity toward Ag + in the presence of various other metal ions in aqueous solution. A series of control compounds were designed and synthesized in order to explore the photoinduced electron transfer (PET) quenching mechanism of NPQ and binding mode of NPQ with Ag +. Moreover, with the NPQ-Ag + complex, I - was easily selectively recognized by a marked fluorescence quenching. The live cell imaging experiments demonstrate that NPQ can be used as a fluorescent probe for monitoring Ag + in living cells.

UR - https://www.scopus.com/pages/publications/84862183375

U2 - 10.1039/c2dt30404j

DO - 10.1039/c2dt30404j

M3 - 文章

C2 - 22572837

AN - SCOPUS:84862183375

SN - 1477-9226

VL - 41

SP - 7212

EP - 7217

JO - Dalton Transactions

JF - Dalton Transactions

IS - 24

ER -

A highly selective and sensitive fluorescence "turn-on" probe for Ag ⁺ in aqueous solution and live cells

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