A highly efficient friedel-crafts reaction of tertiary α- hydroxyesters or α-hydroxyketones to α-quaternary esters or ketones

Long Chen; Jian Zhou

doi:10.1002/asia.201200693

A highly efficient friedel-crafts reaction of tertiary α- hydroxyesters or α-hydroxyketones to α-quaternary esters or ketones

Long Chen
, Jian Zhou^*

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

A catalytic Friedel-Crafts arylation of α-hydroxyesters or α-hydroxyketones with electron-rich aromatic compounds to furnish α-quaternary esters/ketones has been developed. The cheap and easy to handle catalyst HClO ₄ (70 %, aq) was identified as a powerful catalyst for this arylation reaction.

Original language	English
Pages (from-to)	2510-2515
Number of pages	6
Journal	Chemistry - An Asian Journal
Volume	7
Issue number	11
DOIs	https://doi.org/10.1002/asia.201200693
State	Published - Nov 2012

Keywords

Friedel-Crafts reaction
alcohols
heterocycles
homogeneous catalysis
ketones

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10.1002/asia.201200693

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title = "A highly efficient friedel-crafts reaction of tertiary α- hydroxyesters or α-hydroxyketones to α-quaternary esters or ketones",

abstract = "A catalytic Friedel-Crafts arylation of α-hydroxyesters or α-hydroxyketones with electron-rich aromatic compounds to furnish α-quaternary esters/ketones has been developed. The cheap and easy to handle catalyst HClO 4 (70 \%, aq) was identified as a powerful catalyst for this arylation reaction.",

keywords = "Friedel-Crafts reaction, alcohols, heterocycles, homogeneous catalysis, ketones",

author = "Long Chen and Jian Zhou",

year = "2012",

month = nov,

doi = "10.1002/asia.201200693",

language = "英语",

volume = "7",

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AU - Chen, Long

AU - Zhou, Jian

PY - 2012/11

Y1 - 2012/11

N2 - A catalytic Friedel-Crafts arylation of α-hydroxyesters or α-hydroxyketones with electron-rich aromatic compounds to furnish α-quaternary esters/ketones has been developed. The cheap and easy to handle catalyst HClO 4 (70 %, aq) was identified as a powerful catalyst for this arylation reaction.

AB - A catalytic Friedel-Crafts arylation of α-hydroxyesters or α-hydroxyketones with electron-rich aromatic compounds to furnish α-quaternary esters/ketones has been developed. The cheap and easy to handle catalyst HClO 4 (70 %, aq) was identified as a powerful catalyst for this arylation reaction.

KW - Friedel-Crafts reaction

KW - alcohols

KW - heterocycles

KW - homogeneous catalysis

KW - ketones

UR - https://www.scopus.com/pages/publications/84867459848

U2 - 10.1002/asia.201200693

DO - 10.1002/asia.201200693

M3 - 文章

AN - SCOPUS:84867459848

SN - 1861-4728

VL - 7

SP - 2510

EP - 2515

JO - Chemistry - An Asian Journal

JF - Chemistry - An Asian Journal

IS - 11

ER -

A highly efficient friedel-crafts reaction of tertiary α- hydroxyesters or α-hydroxyketones to α-quaternary esters or ketones

Abstract

Keywords

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