TY - JOUR
T1 - A framework of biomarkers for adipose tissue aging
T2 - A consensus statement by the Aging Biomarker Consortium
AU - Aging Biomarker Consortium
AU - Yu, Jian
AU - Zhang, Yankang
AU - Zhang, Ting
AU - Bi, Yan
AU - Chen, Yan
AU - Chen, Zheng
AU - Dai, Zhe
AU - Guo, Feifan
AU - Guo, Lixin
AU - Hu, Cheng
AU - Kong, Xiangqing
AU - Li, Jian
AU - Liu, Pingsheng
AU - Liu, Yong
AU - Qu, Jing
AU - Tang, Qiqun
AU - Wang, Congyi
AU - Wang, Liheng
AU - Wang, Jiqiu
AU - Weng, Jianping
AU - Xu, Aimin
AU - Xu, Lingyan
AU - Zhang, Huijie
AU - Zhao, Jiajun
AU - Zhang, Jingjing
AU - Zhang, Weiqi
AU - Zhao, Tongjin
AU - Zhang, Weiping
AU - Zhu, Zhiming
AU - Liu, Guang Hui
AU - Ning, Guang
AU - Pei, Gang
AU - Qiang, Li
AU - Liu, Feng
AU - Ma, Xinran
N1 - Publisher Copyright:
© 2025 The Author(s).
PY - 2025/10/1
Y1 - 2025/10/1
N2 - Adipose tissue serves as a crucial energy storage and metabolic organ in the human body. With the surging of elderly population in China comes significant challenges in preventing and managing age-associated diseases, while adipose tissue aging represents one of the pivotal initiating events for multi-organ senescence. To address these challenges, the Aging China Biomarkers Consortium (ABC) has established an expert consensus on biomarkers of adipose tissue aging by digesting literature and collecting insights from scientists and clinicians. This consensus provides a comprehensive evaluation of the key changes and characteristics, as well as biomarkers related to adipose tissue aging and proposes a systematic framework categorizing these biomarkers into functional, structural and humoral dimensions. Within each dimension, the ABC recommends clinically and empirically validated biomarkers and parameters for assessing both physiological and pathological changes in adipose tissue during aging, which aims to establish a foundation for future prediction, diagnosis, early warning and treatment for adipose tissue aging and its related diseases, with the ultimate goal of improving adipose tissue health and promoting healthy aging in elderly populations both in China and worldwide.
AB - Adipose tissue serves as a crucial energy storage and metabolic organ in the human body. With the surging of elderly population in China comes significant challenges in preventing and managing age-associated diseases, while adipose tissue aging represents one of the pivotal initiating events for multi-organ senescence. To address these challenges, the Aging China Biomarkers Consortium (ABC) has established an expert consensus on biomarkers of adipose tissue aging by digesting literature and collecting insights from scientists and clinicians. This consensus provides a comprehensive evaluation of the key changes and characteristics, as well as biomarkers related to adipose tissue aging and proposes a systematic framework categorizing these biomarkers into functional, structural and humoral dimensions. Within each dimension, the ABC recommends clinically and empirically validated biomarkers and parameters for assessing both physiological and pathological changes in adipose tissue during aging, which aims to establish a foundation for future prediction, diagnosis, early warning and treatment for adipose tissue aging and its related diseases, with the ultimate goal of improving adipose tissue health and promoting healthy aging in elderly populations both in China and worldwide.
UR - https://www.scopus.com/pages/publications/105019542327
U2 - 10.1093/lifemedi/lnaf027
DO - 10.1093/lifemedi/lnaf027
M3 - 文献综述
AN - SCOPUS:105019542327
SN - 2755-1733
VL - 4
JO - Life Medicine
JF - Life Medicine
IS - 5
M1 - lnaf027
ER -
