A convenient synthesis of the immunosuppressive agent FTY720

Xiangjun Feng; Yuhua Mei; Yu Luo; Wei Lu

doi:10.1007/s00706-011-0582-7

A convenient synthesis of the immunosuppressive agent FTY720

Xiangjun Feng
, Yuhua Mei
, Yu Luo^*
, Wei Lu

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

This paper describes a practical synthetic approach to preparation of an immunosuppressant, FTY720. The key steps involve an iron-catalyzed cross-coupling reaction and a Wittig reaction. The advantages of this synthesis include readily available starting materials, inexpensive reagents, simple operations and good yields.

Original language	English
Pages (from-to)	161-164
Number of pages	4
Journal	Monatshefte fur Chemie
Volume	143
Issue number	1
DOIs	https://doi.org/10.1007/s00706-011-0582-7
State	Published - Jan 2012

Keywords

FTY720
Immunosuppressant
Iron-catalyzed
Synthesis
Wittig reaction

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10.1007/s00706-011-0582-7

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title = "A convenient synthesis of the immunosuppressive agent FTY720",

abstract = "This paper describes a practical synthetic approach to preparation of an immunosuppressant, FTY720. The key steps involve an iron-catalyzed cross-coupling reaction and a Wittig reaction. The advantages of this synthesis include readily available starting materials, inexpensive reagents, simple operations and good yields.",

keywords = "FTY720, Immunosuppressant, Iron-catalyzed, Synthesis, Wittig reaction",

author = "Xiangjun Feng and Yuhua Mei and Yu Luo and Wei Lu",

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AU - Feng, Xiangjun

AU - Mei, Yuhua

AU - Luo, Yu

AU - Lu, Wei

PY - 2012/1

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N2 - This paper describes a practical synthetic approach to preparation of an immunosuppressant, FTY720. The key steps involve an iron-catalyzed cross-coupling reaction and a Wittig reaction. The advantages of this synthesis include readily available starting materials, inexpensive reagents, simple operations and good yields.

AB - This paper describes a practical synthetic approach to preparation of an immunosuppressant, FTY720. The key steps involve an iron-catalyzed cross-coupling reaction and a Wittig reaction. The advantages of this synthesis include readily available starting materials, inexpensive reagents, simple operations and good yields.

KW - FTY720

KW - Immunosuppressant

KW - Iron-catalyzed

KW - Synthesis

KW - Wittig reaction

UR - https://www.scopus.com/pages/publications/84858861934

U2 - 10.1007/s00706-011-0582-7

DO - 10.1007/s00706-011-0582-7

M3 - 文章

AN - SCOPUS:84858861934

SN - 0026-9247

VL - 143

SP - 161

EP - 164

JO - Monatshefte fur Chemie

JF - Monatshefte fur Chemie

IS - 1

ER -

A convenient synthesis of the immunosuppressive agent FTY720

Abstract

Keywords

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