A concise synthesis of nornitidine via nickel- or palladium-catalyzed annulation

Yu Luo; Yuhua Mei; Jianbo Zhang; Wei Lu; Jie Tang

doi:10.1016/j.tet.2006.07.048

A concise synthesis of nornitidine via nickel- or palladium-catalyzed annulation

Yu Luo
, Yuhua Mei
, Jianbo Zhang
, Wei Lu^*
, Jie Tang

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

East China Normal University
CAS - Shanghai Institute of Materia Medica

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

A concise method to synthesize benzo[c]phenanthridine alkaloid, nornitidine, was developed utilizing nickel- or palladium-catalyzed iminoannulation of an internal alkyne. The advantages of this strategy included readily available starting materials, inexpensive reagents, short reaction steps, and good yields.

Original language	English
Pages (from-to)	9131-9134
Number of pages	4
Journal	Tetrahedron
Volume	62
Issue number	39
DOIs	https://doi.org/10.1016/j.tet.2006.07.048
State	Published - 25 Sep 2006

Keywords

Benzo[c]phenanthridine
Catalysis
Isoquinolines
Nickel
Nitidine
Palladium

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10.1016/j.tet.2006.07.048

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title = "A concise synthesis of nornitidine via nickel- or palladium-catalyzed annulation",

abstract = "A concise method to synthesize benzo[c]phenanthridine alkaloid, nornitidine, was developed utilizing nickel- or palladium-catalyzed iminoannulation of an internal alkyne. The advantages of this strategy included readily available starting materials, inexpensive reagents, short reaction steps, and good yields.",

keywords = "Benzo[c]phenanthridine, Catalysis, Isoquinolines, Nickel, Nitidine, Palladium",

author = "Yu Luo and Yuhua Mei and Jianbo Zhang and Wei Lu and Jie Tang",

year = "2006",

month = sep,

day = "25",

doi = "10.1016/j.tet.2006.07.048",

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T1 - A concise synthesis of nornitidine via nickel- or palladium-catalyzed annulation

AU - Luo, Yu

AU - Mei, Yuhua

AU - Zhang, Jianbo

AU - Lu, Wei

AU - Tang, Jie

PY - 2006/9/25

Y1 - 2006/9/25

N2 - A concise method to synthesize benzo[c]phenanthridine alkaloid, nornitidine, was developed utilizing nickel- or palladium-catalyzed iminoannulation of an internal alkyne. The advantages of this strategy included readily available starting materials, inexpensive reagents, short reaction steps, and good yields.

AB - A concise method to synthesize benzo[c]phenanthridine alkaloid, nornitidine, was developed utilizing nickel- or palladium-catalyzed iminoannulation of an internal alkyne. The advantages of this strategy included readily available starting materials, inexpensive reagents, short reaction steps, and good yields.

KW - Benzo[c]phenanthridine

KW - Catalysis

KW - Isoquinolines

KW - Nickel

KW - Nitidine

KW - Palladium

UR - https://www.scopus.com/pages/publications/33746964927

U2 - 10.1016/j.tet.2006.07.048

DO - 10.1016/j.tet.2006.07.048

M3 - 文章

AN - SCOPUS:33746964927

SN - 0040-4020

VL - 62

SP - 9131

EP - 9134

JO - Tetrahedron

JF - Tetrahedron

IS - 39

ER -

A concise synthesis of nornitidine via nickel- or palladium-catalyzed annulation

Abstract

Keywords

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