钯催化的三取代烯烃钯催化的三取代烯烃的对映和非对映选择性氢羧基化反应

Zhen Wang; Kaiwu Dong

doi:10.6023/cjoc202402003

钯催化的三取代烯烃钯催化的三取代烯烃的对映和非对映选择性氢羧基化反应

Translated title of the contribution: Pd-Catalyzed Enantio- and Diastereo-selective Hydrocarboxylation of Trisubstituted Alkenes

Zhen Wang
, Kaiwu Dong^*

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

Abstract

A palladium-catalyzed asymmetric intermolecular hydrocarboxylation of trisubstituted alkenes was reported, which afforded a series of succinic acid derivatives containing two chiral centers with moderate to excellent yields, enantioselectivity, and high diastereoselectivity. The resulting dimethyl succinates can be easily converted to optically active γ-butyrolactones, demonstrating the potential application of this method.

Translated title of the contribution	Pd-Catalyzed Enantio- and Diastereo-selective Hydrocarboxylation of Trisubstituted Alkenes
Original language	Chinese (Traditional)
Pages (from-to)	3249-3257
Number of pages	9
Journal	Chinese Journal of Organic Chemistry
Volume	44
Issue number	10
DOIs	https://doi.org/10.6023/cjoc202402003
State	Published - 25 Oct 2024

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title = "钯催化的三取代烯烃钯催化的三取代烯烃的对映和非对映选择性氢羧基化反应",

abstract = "A palladium-catalyzed asymmetric intermolecular hydrocarboxylation of trisubstituted alkenes was reported, which afforded a series of succinic acid derivatives containing two chiral centers with moderate to excellent yields, enantioselectivity, and high diastereoselectivity. The resulting dimethyl succinates can be easily converted to optically active γ-butyrolactones, demonstrating the potential application of this method.",

keywords = "alkene, asymmetric, carbon monoxide, hydrocarbonylation, palladium, succinic acid",

author = "Zhen Wang and Kaiwu Dong",

note = "Publisher Copyright: {\textcopyright} 2024 Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences.",

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T1 - 钯催化的三取代烯烃钯催化的三取代烯烃的对映和非对映选择性氢羧基化反应

AU - Wang, Zhen

AU - Dong, Kaiwu

PY - 2024/10/25

Y1 - 2024/10/25

N2 - A palladium-catalyzed asymmetric intermolecular hydrocarboxylation of trisubstituted alkenes was reported, which afforded a series of succinic acid derivatives containing two chiral centers with moderate to excellent yields, enantioselectivity, and high diastereoselectivity. The resulting dimethyl succinates can be easily converted to optically active γ-butyrolactones, demonstrating the potential application of this method.

AB - A palladium-catalyzed asymmetric intermolecular hydrocarboxylation of trisubstituted alkenes was reported, which afforded a series of succinic acid derivatives containing two chiral centers with moderate to excellent yields, enantioselectivity, and high diastereoselectivity. The resulting dimethyl succinates can be easily converted to optically active γ-butyrolactones, demonstrating the potential application of this method.

KW - alkene

KW - asymmetric

KW - carbon monoxide

KW - hydrocarbonylation

KW - palladium

KW - succinic acid

UR - https://www.scopus.com/pages/publications/85210990262

U2 - 10.6023/cjoc202402003

DO - 10.6023/cjoc202402003

M3 - 文章

AN - SCOPUS:85210990262

SN - 0253-2786

VL - 44

SP - 3249

EP - 3257

JO - Chinese Journal of Organic Chemistry

JF - Chinese Journal of Organic Chemistry

IS - 10

ER -

钯催化的三取代烯烃钯催化的三取代烯烃的对映和非对映选择性氢羧基化反应

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